An excellent response to tofacitinib in a Brazilian adolescent patient with alopecia areata: A case report and a review of the literature

被引：11

作者：

Ferreira, Rachel Berbert ^{[1
]}

Ferreira, Sineida Berbert ^{[2
]}

Scheinberg, Morton Aaron ^{[3
]}

机构：

[1] Ctr Univ Cesumar, Fac Med, Maringa, Parana, Brazil

[2] Private Clin Dermatol Dra Sineida Berbert Ferreir, Maringa, Parana, Brazil

[3] Hosp Israelita Albert Einstein San Paulo, Sao Paulo, SP, Brazil

来源：

CLINICAL CASE REPORTS | 2019年 / 7卷 / 12期

关键词：

adolescent; alopecia areata; dermatology; hair loss; JAK inhibitors; tofacitinib; ORAL TOFACITINIB; UNIVERSALIS; EXPERIENCE;

D O I：

10.1002/ccr3.2484

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Alopecia areata is a common autoimmune disease, with a negative impact in health-related quality of life, especially when affecting children and adolescents. Current medical therapies, mainly for severe disease, are not effective. There are no FDA (Food and Drug Administration)- or ANVISA (Agencia Nacional de Vigilancia Sanitaria)-approved therapy for children with alopecia areata. JAK inhibitors are emerging as a promising therapy.

引用

页码：2539 / 2542

页数：4

共 12 条

[1] Experience with oral tofacitinib in 8 adolescent patients with alopecia universalis [J].

Castelo-Soccio, Leslie .

JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY, 2017, 76 (04) :754-755

[2] Comorbidity profiles among patients with alopecia areata: The importance of onset age, a nationwide population-based study [J].

Chu, Szu-Ying ;

Chen, Yi-Ju ;

Tseng, Wei-Cheng ;

Lin, Ming-Wei ;

Chen, Tzeng-Ji ;

Hwang, Chian-Yaw ;

Chen, Chih-Chiang ;

Lee, Ding-Dar ;

Chang, Yun-Ting ;

Wang, Wen-Jen ;

Liu, Han-Nan .

JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY, 2011, 65 (05) :949-956

[3] Tofacitinib for the treatment of alopecia areata in preadolescent children [J].

Craiglow, Brittany G. ;

King, Brett A. .

JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY, 2019, 80 (02) :568-570

[4] Tofacitinib for the treatment of alopecia areata and variants in adolescents [J].

Craiglow, Brittany G. ;

Liu, Lucy Y. ;

King, Brett A. .

JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY, 2017, 76 (01) :29-32

[5] Killing Two Birds with One Stone: Oral Tofacitinib Reverses Alopecia Universalis in a Patient with Plaque Psoriasis [J].

Craiglow, Brittany G. ;

King, Brett A. .

JOURNAL OF INVESTIGATIVE DERMATOLOGY, 2014, 134 (12) :2988-2990

[6] Safety and efficacy of the JAK inhibitor tofacitinib citrate in patients with alopecia areata [J].

Crispin, Milene Kennedy ;

Ko, Justin M. ;

Craiglow, Brittany G. ;

Li, Shufeng ;

Shankar, Gautam ;

Urban, Jennifer R. ;

Chen, James C. ;

Cerise, Jane E. ;

Jabbari, Ali ;

Winge, Marten C. G. ;

Marinkovich, M. Peter ;

Christiano, Angela M. ;

Oro, Anthony E. ;

King, Brett A. .

JCI INSIGHT, 2016, 1 (15)

[7] Remarkable Improvement of Nail Changes in Alopecia Areata Universalis with 10 Months of Treatment with Tofacitinib: A Case Report [J].

Ferreira, Sineida Berbert ;

Scheinberg, Morton ;

Steiner, Denise ;

Steiner, Tatiana ;

Bedin, Gustavo Longhi ;

Ferreira, Rachel Berbert .

CASE REPORTS IN DERMATOLOGY, 2016, 8 (03) :262-266

[8] Treatment of an alopecia areata patient with tofacitinib results in regrowth of hair and changes in serum and skin biomarkers [J].

Jabbari, Ali ;

Nhan Nguyen ;

Cerise, Jane E. ;

Ulerio, Grace ;

de Jong, Annemieke ;

Clynes, Raphael ;

Christiano, Angela M. ;

Mackay-Wiggan, Julian .

EXPERIMENTAL DERMATOLOGY, 2016, 25 (08) :642-643

[9] Topical 2% tofacitinib for children with alopecia areata, alopecia totalis, and alopecia universalis [J].

Putterman, Elana ;

Castelo-Soccio, Leslie .

JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY, 2018, 78 (06) :1207-+

[10] Brazilian Experience of the Treatment of Alopecia Universalis with the Novel Antirheumatic Therapy Tofacitinib: A Case Series [J].

Scheinberg, Morton ;

de Lucena Couto Ocea, Regina Adalva ;

Cruz, Boris Afonso ;

Ferreira, Sineida Berbert .

RHEUMATOLOGY AND THERAPY, 2017, 4 (02) :503-508

← 1 2 →