Fe2+-catalyzed heterolytic RO-OH bond cleavage and substrate oxidation:: A functional synthetic non-heme iron monooxygenase system

被引：57

作者：

Foster, TL ^{[1
]}

Caradonna, JP ^{[1
]}

机构：

[1] Boston Univ, Dept Chem, Boston, MA 02215 USA

来源：

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY | 2003年 / 125卷 / 13期

关键词：

D O I：

10.1021/ja0286268

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

The reaction of [Fe22+(H2Hbamb)2(N-MeIm)2], [1], a binuclear, non-heme iron complex, with 2-methyl-1-phenylprop-2-yl hydroperoxide (MPPH) shows that [1] induces heterolytic cleavage of the peroxy O-O bond. Catalytic atom transfer reactions (1:MPPH:PhSMe 1:596:6011) resulted in the highly efficient (99 ± 1%), catalytic oxidation of phenyl methyl sulfide to phenyl methyl sulfoxide/sulfone (T.N. = 500/11 respectively) and cyclohexane to cyclohexanol/cyclohexanone (T.N. = 230/5 respectively) showing the highly efficient, catalytic capacity of [1] to carry out oxygen insertion chemistry. Copyright © 2003 American Chemical Society.

引用

页码：3678 / 3679

页数：2

共 13 条

[1] A MECHANISTIC PROBE FOR OXYGEN ACTIVATION BY METAL-COMPLEXES AND HYDROPEROXIDES AND ITS APPLICATION TO ALKANE FUNCTIONALIZATION BY [FE(III)CL(2)TRIS(2-PYRIDINYLMETHYL)AMINE](+)BF4- [J].