RELATIONSHIP OF LEPTIN HORMONE WITH INSULIN AND GLUCOSE IN ARABIAN CAMEL (Camelus dromedarius)

The aim of current study was to know relationship of leptin hormone with insulin and glucose in Arabian camel (Camelus dromedarius). Two hundreds and forty male and female camels were used and divided into 3 groups according age (below 1 year, 1-3 years and above 3 years) for both sex and season (summer and winter). Blood samples were collected and plasma was separated. Leptin and insulin hormones were determined immunoenzymatically on ELISA and Elecsys systems, respectively. Glucose was estimated enzymatically by Reflotron system. Leptin levels were affected by season variation, i.e. its level increases in winter than summer in female and vice versa in males. There was positive correlation between leptin and age in males and negative one in females. A synchronised increase in level of leptin and insulin was noticed with age advancement in males and decrease of those levels in females. Season variations had effects on glucose and insulin in camel plasma. There was an increase of both in male at winter than summer, while glucose and insulin levels increased in female at summer than winter. The results revealed that there was negative relation between glucose and insulin levels with age progression.