Accuracy of theoretical IOL formulas for Panoptix intraocular lens according to axial length

The accuracy of intraocular lens (IOL) calculations is suboptimal for long or short eyes, which results in a low visual quality after multifocal IOL implantation. The purpose of the present study is to evaluate the accuracy of IOL formulas (Barrett Universal II, SRK/T, Holladay 1, Hoffer Q, and Haigis) for the Acrysof IQ Panoptix TFNT IOL (Alcon Laboratories, Inc, Fort Worth, Texas, United States) implantation based on the axial length (AXL) from a large cohort of 2018 cases and identify the factors that are associated with a high mean absolute error (MAE). The Barrett Universal II showed the lowest MAE in the normal AXL group (0.30 +/- 0.23), whereas the Holladay 1 and Hoffer Q showed the lowest MAE in the short AXL group (0.32 +/- 0.22 D and 0.32 +/- 0.21 D, respectively). The Haigis showed the lowest MAE in the long AXL group (0.24 +/- 0.19 D). The Barrett Universal II did not perform well in short AXL eyes with higher astigmatism (P=0.013), wider white-to-white (WTW; P<0.001), and shorter AXL (P=0.016). Study results suggest that the Barrett Universal II performed best for the TFNT IOL in the overall study population, except for the eyes with short AXL, particularly when the eyes had higher astigmatism, wider WTW, and shorter AXL.