Radical scavenging potential of compounds isolated from Vitex agnus-castus

被引：33

作者：

Azizuddin ^{[1
]}

Makhmoor, Talat ^{[2
]}

Choudhary, Muhammad Iqbal ^{[2
]}

机构：

[1] Jinnah Govt Coll, Dept Chem, Karachi 74600, Pakistan

[2] Univ Karachi, Int Ctr Chem & Biol Sci, HEJ Res Inst Chem, Karachi 75270, Pakistan

来源：

TURKISH JOURNAL OF CHEMISTRY | 2010年 / 34卷 / 01期

关键词：

Vitex agnus-castus; Verbenaceae; antioxidant; DPPH radical scavenging activity; flavonoids; MAGNETIC-RESONANCE;

D O I：

10.3906/kim-0805-46

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Nine secondary metabolites-artemetin (1), casticin (2), 3-hydroxy-5,6,7,4'-tetramethoxy flavone U(3), penduletin (4), p-hydroxybenzoic acid (5), methyl 3,4-dihydroxybenzoate (6), methyl isovanillate (7), vanillic acid (8), and 3,4-dihydroxybenzoic acid (9)-were isolated from a folkloric medicinal plant, Vitex agnus-castus. The structures of compounds 1-9 were identified using spectroscopic techniques. Compound 7 was isolated for the first time from this plant. These compounds were screened for their antioxidant activity. Compounds 6 and 9 exhibited significant activity against the DPPH free radical.

引用

页码：119 / 126

页数：8

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