Prognostic value of morphology and hormone receptor status in breast cancer -: a population-based study

被引:34
|
作者
Allemani, C
Sant, M
Berrino, F
Aareleid, T
Chaplain, G
Coebergh, JW
Colonna, M
Contiero, P
Danzon, A
Federico, M
Gafà, L
Grosclaude, P
Hédelin, G
Macè-Lesech, J
Garcia, CM
Paci, E
Raverdy, N
Tretarre, B
Williams, EMI
机构
[1] Ist Nazl Studio & Cura Tumori, Epidemiol Unit, I-20133 Milan, Italy
[2] Inst Clin & Expt Med, Dept Epidemiol & Biostat, EE-11619 Tallinn, Estonia
[3] N Estonian Reg Hosp Fdn Canc Ctr, Estonian Canc Registry, EE-11619 Tallinn, Estonia
[4] Fac Med, Ctr Univ Epidemiol Populat, Cote dOr Breast & Gynaecol Canc Registry, F-21000 Dijon, France
[5] Eindhoven Canc Registry, Comprehens Canc Ctr S, NL-5600 EA Eindhoven, Netherlands
[6] Isere Canc Registry, F-38240 Meylan, France
[7] Ist Nazl Studio & Cura Tumori, Lombardy Canc Registry, I-20133 Milan, Italy
[8] CHU Besancon, Doubs Canc Registry, F-25030 Besancon, France
[9] Policlin, Modena Canc Registry, I-41100 Modena, Italy
[10] Ragusa Canc Registry, I-97100 Ragusa, Italy
[11] Tam Canc Registry Rech Epidemiol & Prevent, F-81001 Albi, France
[12] Fac Med Strasbourg, Bas Rhin Canc Registry, Lab Epidemiol & Sante Publ, F-67085 Strasbourg, France
[13] Ctr Francois Baclesse, Calvados Canc Registry, F-14021 Caen, France
[14] Escuela Andaluza SAlud Publ, Granada Canc Registry, E-18080 Granada, Spain
[15] Ao Careggi CSPO, UO Epidemiol Clin & Descritt, Tuscany Canc Registry, I-50135 Florence, Italy
[16] CHR Nord, Assoc Rech Epidemiol Picardie, Somme Canc Registry, F-80054 Amiens 1, France
[17] Herault Canc Registry, F-34298 Montpellier 5, France
[18] Univ Liverpool, Mersey Canc Registry, Liverpool L69 3GB, Merseyside, England
关键词
breast cancer; population-based studies; relative survival; predictive factors; relative excess risk of death;
D O I
10.1038/sj.bjc.6602153
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
We analysed the 5-year relative survival among 4473 breast cancer cases diagnosed in 1990-1992 from cancer registries in Estonia, France, Italy, Spain, the Netherlands and the UK. Among eight categories based on ICD-O codes (infiltrating ductal carcinoma, lobular plus mixed carcinoma, comedocarcinoma, 'special types', medullary carcinoma, not otherwise specified (NOS) carcinoma, other carcinoma and cancer without microscopic confirmation), the 5-year relative survival ranged from 66% (95% CI 61-71) for NOS carcinoma to 95% (95% CI 90-100) for special types (tubular, apocrine, cribriform, papillary, mucinous and signet ring cell); 27% (95% CI 18-36) for cases without microscopic confirmation. Differences in 5-year relative survival by tumor morphology and hormone receptor status were modelled using a multiple regression approach based on generalised linear models. Morphology and hormone receptor status were confirmed as significant survival predictors in this population-based study, even after adjusting for age and stage at diagnosis.
引用
收藏
页码:1263 / 1268
页数:6
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