Monoclonal Antibodies for Multiple Sclerosis Treatment

被引:1
|
作者
Palavra, Filipe [1 ,2 ]
机构
[1] Univ Coimbra, Fac Med, Inst Biomed Imaging & Life Sci, CNC,IBILI Res Unit, Coimbra, Portugal
[2] Univ Coimbra, Fac Med, Inst Nucl Sci Appl Hlth ICNAS, Coimbra, Portugal
来源
ACTA MEDICA PORTUGUESA | 2015年 / 28卷 / 05期
关键词
Antibodies; Monoclonal; Clinical Trials; Multiple Sclerosis; HIGH-YIELD PROCESS; DOUBLE-BLIND; DISEASE-ACTIVITY; ENDOGENOUS RETROVIRUS; NATALIZUMAB; DACLIZUMAB; ALEMTUZUMAB; MULTICENTER; THERAPY; CELLS;
D O I
10.20344/amp.6486
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Since their introduction in medical therapy, in the last quarter of the 20th century, monoclonal antibodies have gained an increasing importance in the treatment of various diseases. Neurology has been one of the medical specialties benefiting of the therapeutic potential of these monoclonal antibodies and certain neurological conditions may now contain such drugs in their therapeutic algorithms. Multiple sclerosis is one of these diseases and, in addition to the monoclonal antibodies already licensed for clinical use, several others are in development for future utilization in this specific area. The future will certainly pass through this kind of drugs and, in this article, a review of the most relevant data related to monoclonal antibodies already in use and also in clinical development for multiple sclerosis treatment will be performed.
引用
收藏
页码:640 / 651
页数:12
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