Drug targeting;
graphene;
honeycomb lattice;
nanomaterial;
one atom thickness;
two-dimensional sheet;
SENSORS;
FILMS;
OXIDE;
GAS;
D O I:
10.2174/1389450117666160709023425
中图分类号:
R9 [药学];
学科分类号:
1007 ;
摘要:
Graphene, a one-atom thick, two-dimensional sheets of sp(2) hybridized carbon atoms packed in a hexagonal lattice with a Caron-Carbon distance of about 0.142 nm. Its extended honeycomb network forms the basic building block of other important allotropes; it can be stacked to form 3-Dgraphite, rolled to form 1-D-nanotubes and wrapped to form 0-D-fullerenes. Long-range pi conjugation in graphene results in its extraordinary thermal, mechanical and electrical properties, which have been the interest of many theoretical studies and recently became an exciting area for scientists. Graphene is impermeable to gas and liquids, has excellent thermal conductivity and higher current density in comparison to other most effective materials. All of its exceptional properties have opened up new avenues for the use of graphene in nano-devices and nano-systems, which initiated its prominent use as a material for drug targeting. In addition, several fabrication techniques are outlined, starting from the mechanical exfoliation of high-quality graphene to the direct growth on silicon carbide or metal substrates and from the chemical routes utilizing graphene oxide to the newly developed approach at the molecular level. By this article reviewers intend to emphasize on unique properties, fabrication techniques and updated applications of graphene. In addition, we discuss about the potential of graphene in drug targeting in fields of nanotechnology, biomedical engineering and technology and its use for innovations in various fields such as electronics and photonics.
机构:
Univ Calif Los Angeles, Dept Chem & Biochem, Los Angeles, CA 90095 USA
Univ Calif Los Angeles, Calif NanoSyst Inst, Los Angeles, CA 90095 USAUniv Calif Los Angeles, Dept Chem & Biochem, Los Angeles, CA 90095 USA
Allen, Matthew J.
;
Tung, Vincent C.
论文数: 0引用数: 0
h-index: 0
机构:
Univ Calif Los Angeles, Calif NanoSyst Inst, Los Angeles, CA 90095 USA
Univ Calif Los Angeles, Dept Mat Sci & Engn, Los Angeles, CA 90095 USAUniv Calif Los Angeles, Dept Chem & Biochem, Los Angeles, CA 90095 USA
Tung, Vincent C.
;
Kaner, Richard B.
论文数: 0引用数: 0
h-index: 0
机构:
Univ Calif Los Angeles, Dept Chem & Biochem, Los Angeles, CA 90095 USA
Univ Calif Los Angeles, Calif NanoSyst Inst, Los Angeles, CA 90095 USA
Univ Calif Los Angeles, Dept Mat Sci & Engn, Los Angeles, CA 90095 USAUniv Calif Los Angeles, Dept Chem & Biochem, Los Angeles, CA 90095 USA
机构:
Univ Malaya, Fac Engn, Dept Mech Engn, Kuala Lumpur 50603, MalaysiaUniv Malaya, Fac Engn, Dept Mech Engn, Kuala Lumpur 50603, Malaysia
Baradaran, S.
;
Moghaddam, E.
论文数: 0引用数: 0
h-index: 0
机构:
Univ Malaya, Fac Med, Trop Infect Dis Res & Educ Ctr, Dept Med Microbiol, Kuala Lumpur 50603, MalaysiaUniv Malaya, Fac Engn, Dept Mech Engn, Kuala Lumpur 50603, Malaysia
Moghaddam, E.
;
论文数: 引用数:
h-index:
机构:
Basirun, W. J.
;
Mehrali, M.
论文数: 0引用数: 0
h-index: 0
机构:
Univ Malaya, Fac Engn, Dept Mech Engn, Kuala Lumpur 50603, Malaysia
Univ Malaya, Fac Engn, Dept Biomed Engn, Kuala Lumpur 50603, MalaysiaUniv Malaya, Fac Engn, Dept Mech Engn, Kuala Lumpur 50603, Malaysia
Mehrali, M.
;
论文数: 引用数:
h-index:
机构:
Sookhakian, M.
;
Hamdi, M.
论文数: 0引用数: 0
h-index: 0
机构:
Univ Malaya, Ctr Adv Mfg & Mat Proc, Kuala Lumpur 50603, MalaysiaUniv Malaya, Fac Engn, Dept Mech Engn, Kuala Lumpur 50603, Malaysia
Hamdi, M.
;
Moghaddam, M. R. Nakhaei
论文数: 0引用数: 0
h-index: 0
机构:
Univ Malaya, Fac Med, Dept Orthoped Surg, Kuala Lumpur 50603, MalaysiaUniv Malaya, Fac Engn, Dept Mech Engn, Kuala Lumpur 50603, Malaysia
Moghaddam, M. R. Nakhaei
;
Alias, Y.
论文数: 0引用数: 0
h-index: 0
机构:
Univ Malaya, Fac Sci, Dept Chem, Kuala Lumpur 50603, MalaysiaUniv Malaya, Fac Engn, Dept Mech Engn, Kuala Lumpur 50603, Malaysia
机构:
Columbia Univ, Dept Phys, New York, NY 10027 USAColumbia Univ, Dept Phys, New York, NY 10027 USA
Bolotin, K. I.
;
Sikes, K. J.
论文数: 0引用数: 0
h-index: 0
机构:
Columbia Univ, Dept Appl Phys, New York, NY 10027 USAColumbia Univ, Dept Phys, New York, NY 10027 USA
Sikes, K. J.
;
Jiang, Z.
论文数: 0引用数: 0
h-index: 0
机构:
Columbia Univ, Dept Phys, New York, NY 10027 USA
Natl High Magnet Field Lab, Tallahassee, FL 32310 USAColumbia Univ, Dept Phys, New York, NY 10027 USA
Jiang, Z.
;
Klima, M.
论文数: 0引用数: 0
h-index: 0
机构:
Columbia Univ, Dept Mech Engn, New York, NY 10027 USAColumbia Univ, Dept Phys, New York, NY 10027 USA
Klima, M.
;
Fudenberg, G.
论文数: 0引用数: 0
h-index: 0
机构:
Columbia Univ, Dept Phys, New York, NY 10027 USAColumbia Univ, Dept Phys, New York, NY 10027 USA
Fudenberg, G.
;
Hone, J.
论文数: 0引用数: 0
h-index: 0
机构:
Columbia Univ, Dept Mech Engn, New York, NY 10027 USAColumbia Univ, Dept Phys, New York, NY 10027 USA
Hone, J.
;
Kim, P.
论文数: 0引用数: 0
h-index: 0
机构:
Columbia Univ, Dept Phys, New York, NY 10027 USAColumbia Univ, Dept Phys, New York, NY 10027 USA
Kim, P.
;
Stormer, H. L.
论文数: 0引用数: 0
h-index: 0
机构:
Columbia Univ, Dept Phys, New York, NY 10027 USA
Columbia Univ, Dept Appl Phys, New York, NY 10027 USA
Alcatel Lucent Technol, Bell Labs, Murray Hill, NJ 07974 USAColumbia Univ, Dept Phys, New York, NY 10027 USA
机构:
Columbia Univ, Dept Phys, New York, NY 10027 USAColumbia Univ, Dept Phys, New York, NY 10027 USA
Bolotin, K. I.
;
Sikes, K. J.
论文数: 0引用数: 0
h-index: 0
机构:
Columbia Univ, Dept Appl Phys, New York, NY 10027 USAColumbia Univ, Dept Phys, New York, NY 10027 USA
Sikes, K. J.
;
Hone, J.
论文数: 0引用数: 0
h-index: 0
机构:
Columbia Univ, Dept Mech Engn, New York, NY 10027 USAColumbia Univ, Dept Phys, New York, NY 10027 USA
Hone, J.
;
Stormer, H. L.
论文数: 0引用数: 0
h-index: 0
机构:
Columbia Univ, Dept Phys, New York, NY 10027 USA
Columbia Univ, Dept Appl Phys, New York, NY 10027 USA
Bell Labs, Alcatel Lucent Technol, Murray Hill, NJ 07974 USAColumbia Univ, Dept Phys, New York, NY 10027 USA
Stormer, H. L.
;
Kim, P.
论文数: 0引用数: 0
h-index: 0
机构:
Columbia Univ, Dept Phys, New York, NY 10027 USAColumbia Univ, Dept Phys, New York, NY 10027 USA
机构:
Univ Calif Los Angeles, Dept Chem & Biochem, Los Angeles, CA 90095 USA
Univ Calif Los Angeles, Calif NanoSyst Inst, Los Angeles, CA 90095 USAUniv Calif Los Angeles, Dept Chem & Biochem, Los Angeles, CA 90095 USA
Allen, Matthew J.
;
Tung, Vincent C.
论文数: 0引用数: 0
h-index: 0
机构:
Univ Calif Los Angeles, Calif NanoSyst Inst, Los Angeles, CA 90095 USA
Univ Calif Los Angeles, Dept Mat Sci & Engn, Los Angeles, CA 90095 USAUniv Calif Los Angeles, Dept Chem & Biochem, Los Angeles, CA 90095 USA
Tung, Vincent C.
;
Kaner, Richard B.
论文数: 0引用数: 0
h-index: 0
机构:
Univ Calif Los Angeles, Dept Chem & Biochem, Los Angeles, CA 90095 USA
Univ Calif Los Angeles, Calif NanoSyst Inst, Los Angeles, CA 90095 USA
Univ Calif Los Angeles, Dept Mat Sci & Engn, Los Angeles, CA 90095 USAUniv Calif Los Angeles, Dept Chem & Biochem, Los Angeles, CA 90095 USA
机构:
Univ Malaya, Fac Engn, Dept Mech Engn, Kuala Lumpur 50603, MalaysiaUniv Malaya, Fac Engn, Dept Mech Engn, Kuala Lumpur 50603, Malaysia
Baradaran, S.
;
Moghaddam, E.
论文数: 0引用数: 0
h-index: 0
机构:
Univ Malaya, Fac Med, Trop Infect Dis Res & Educ Ctr, Dept Med Microbiol, Kuala Lumpur 50603, MalaysiaUniv Malaya, Fac Engn, Dept Mech Engn, Kuala Lumpur 50603, Malaysia
Moghaddam, E.
;
论文数: 引用数:
h-index:
机构:
Basirun, W. J.
;
Mehrali, M.
论文数: 0引用数: 0
h-index: 0
机构:
Univ Malaya, Fac Engn, Dept Mech Engn, Kuala Lumpur 50603, Malaysia
Univ Malaya, Fac Engn, Dept Biomed Engn, Kuala Lumpur 50603, MalaysiaUniv Malaya, Fac Engn, Dept Mech Engn, Kuala Lumpur 50603, Malaysia
Mehrali, M.
;
论文数: 引用数:
h-index:
机构:
Sookhakian, M.
;
Hamdi, M.
论文数: 0引用数: 0
h-index: 0
机构:
Univ Malaya, Ctr Adv Mfg & Mat Proc, Kuala Lumpur 50603, MalaysiaUniv Malaya, Fac Engn, Dept Mech Engn, Kuala Lumpur 50603, Malaysia
Hamdi, M.
;
Moghaddam, M. R. Nakhaei
论文数: 0引用数: 0
h-index: 0
机构:
Univ Malaya, Fac Med, Dept Orthoped Surg, Kuala Lumpur 50603, MalaysiaUniv Malaya, Fac Engn, Dept Mech Engn, Kuala Lumpur 50603, Malaysia
Moghaddam, M. R. Nakhaei
;
Alias, Y.
论文数: 0引用数: 0
h-index: 0
机构:
Univ Malaya, Fac Sci, Dept Chem, Kuala Lumpur 50603, MalaysiaUniv Malaya, Fac Engn, Dept Mech Engn, Kuala Lumpur 50603, Malaysia
机构:
Columbia Univ, Dept Phys, New York, NY 10027 USAColumbia Univ, Dept Phys, New York, NY 10027 USA
Bolotin, K. I.
;
Sikes, K. J.
论文数: 0引用数: 0
h-index: 0
机构:
Columbia Univ, Dept Appl Phys, New York, NY 10027 USAColumbia Univ, Dept Phys, New York, NY 10027 USA
Sikes, K. J.
;
Jiang, Z.
论文数: 0引用数: 0
h-index: 0
机构:
Columbia Univ, Dept Phys, New York, NY 10027 USA
Natl High Magnet Field Lab, Tallahassee, FL 32310 USAColumbia Univ, Dept Phys, New York, NY 10027 USA
Jiang, Z.
;
Klima, M.
论文数: 0引用数: 0
h-index: 0
机构:
Columbia Univ, Dept Mech Engn, New York, NY 10027 USAColumbia Univ, Dept Phys, New York, NY 10027 USA
Klima, M.
;
Fudenberg, G.
论文数: 0引用数: 0
h-index: 0
机构:
Columbia Univ, Dept Phys, New York, NY 10027 USAColumbia Univ, Dept Phys, New York, NY 10027 USA
Fudenberg, G.
;
Hone, J.
论文数: 0引用数: 0
h-index: 0
机构:
Columbia Univ, Dept Mech Engn, New York, NY 10027 USAColumbia Univ, Dept Phys, New York, NY 10027 USA
Hone, J.
;
Kim, P.
论文数: 0引用数: 0
h-index: 0
机构:
Columbia Univ, Dept Phys, New York, NY 10027 USAColumbia Univ, Dept Phys, New York, NY 10027 USA
Kim, P.
;
Stormer, H. L.
论文数: 0引用数: 0
h-index: 0
机构:
Columbia Univ, Dept Phys, New York, NY 10027 USA
Columbia Univ, Dept Appl Phys, New York, NY 10027 USA
Alcatel Lucent Technol, Bell Labs, Murray Hill, NJ 07974 USAColumbia Univ, Dept Phys, New York, NY 10027 USA
机构:
Columbia Univ, Dept Phys, New York, NY 10027 USAColumbia Univ, Dept Phys, New York, NY 10027 USA
Bolotin, K. I.
;
Sikes, K. J.
论文数: 0引用数: 0
h-index: 0
机构:
Columbia Univ, Dept Appl Phys, New York, NY 10027 USAColumbia Univ, Dept Phys, New York, NY 10027 USA
Sikes, K. J.
;
Hone, J.
论文数: 0引用数: 0
h-index: 0
机构:
Columbia Univ, Dept Mech Engn, New York, NY 10027 USAColumbia Univ, Dept Phys, New York, NY 10027 USA
Hone, J.
;
Stormer, H. L.
论文数: 0引用数: 0
h-index: 0
机构:
Columbia Univ, Dept Phys, New York, NY 10027 USA
Columbia Univ, Dept Appl Phys, New York, NY 10027 USA
Bell Labs, Alcatel Lucent Technol, Murray Hill, NJ 07974 USAColumbia Univ, Dept Phys, New York, NY 10027 USA
Stormer, H. L.
;
Kim, P.
论文数: 0引用数: 0
h-index: 0
机构:
Columbia Univ, Dept Phys, New York, NY 10027 USAColumbia Univ, Dept Phys, New York, NY 10027 USA