Radiotherapy in soft-tissue sarcoma of the extremities

被引：13
作者：
Correa, R. [1 ]
Gomez-Millan, J. [1 ]
Lobato, M. [1 ]
Fernandez, A. [1 ]
Ordonez, R. [1 ]
Castro, C. [1 ]
Lupianez, Y. [1 ]
Medina, J. A. [1 ]
机构：
[1] Hosp Univ Virgen Victoria, Serv Oncol Radioterap, Campus Univ Teatinos S-N, Malaga 29010, Spain
来源：
CLINICAL & TRANSLATIONAL ONCOLOGY | 2018年 / 20卷 / 09期
关键词：
Soft-tissue sarcoma; Preoperative radiotherapy; Postoperative radiotherapy; Chemotherapy; Multikinase inhibitor; Conservative surgery; MODULATED RADIATION-THERAPY; PHASE-I TRIAL; NEOADJUVANT CHEMOTHERAPY; HIGH-RISK; ADJUVANT CHEMOTHERAPY; HIGH-GRADE; POSTOPERATIVE RADIOTHERAPY; RANDOMIZED-TRIAL; LOCAL RECURRENCE; SPARING SURGERY;
D O I：
10.1007/s12094-018-1848-x
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
Sarcomas are an infrequent and heterogeneous group of neoplasia. Surgery with or without associated radiotherapy (RT) is the basic treatment for this type of tumour. To increase the therapeutic ratio (the index between cytotoxic effects in tumours and normal tissue complications with a certain dose of radiation), new advances are being investigated to increase local and distant control and to decrease the morbidity of the treatment. The aim of this review was to analyse the different strategies, based on technology and biology, which are being investigated to increase the therapeutic ratio of this disease.
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收藏
页码：1127 / 1135
页数：9
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