Amaryllidaceae and Sceletium alkaloids

被引:101
作者
Jin, Zhong [1 ]
机构
[1] Nankai Univ, State Key Lab Elemento Organ Chem, Tianjin 300071, Peoples R China
[2] Nankai Univ, Inst Elemento Organ Chem, Tianjin 300071, Peoples R China
关键词
D O I
10.1039/b502163b
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
A great number of natural products, especially alkaloids, which exhibit a range of biological activities including acetylcholinesterase inhibition and antineoplastic, cardiovascular and immunostimulatory activities, have been isolated from the plants of the Amaryllidaceae family. This review summarizes isolation, biological activity, and synthetic studies of these alkaloids. The primary biosynthetic pathways of each type of alkaloids are also proposed.
引用
收藏
页码:886 / 905
页数:20
相关论文
共 122 条
[61]   Accurate product ion mass spectra of galanthamine derivatives [J].
Jegorov, A ;
Buchta, M ;
Sedmera, P ;
Kuzma, M ;
Havlicek, V .
JOURNAL OF MASS SPECTROMETRY, 2006, 41 (04) :544-548
[62]   Amaryllidaceae and Sceletium alkaloids [J].
Jin, Z .
NATURAL PRODUCT REPORTS, 2005, 22 (01) :111-126
[63]  
Kaya G. I., 2004, TURKISH J PHARM SCI, V1, P105
[64]   Quantitative and cytotoxic activity determinations on Galanthus nivalis subsp cilicicus [J].
Kaya, GI ;
Gözler, B .
FITOTERAPIA, 2005, 76 (3-4) :340-343
[65]   (-)-capnoidine and (+)-bulbocapnine from an Amaryllidaceae species, Galanthus nivalis subsp cilicicus [J].
Kaya, GI ;
Unver, N ;
Gözler, B ;
Bastida, J .
BIOCHEMICAL SYSTEMATICS AND ECOLOGY, 2004, 32 (11) :1059-1062
[66]   Pancratistatin causes early activation of caspase-3 and the flipping of phosphatidyl serine followed by rapid apoptosis specifically in human lymphoma cells [J].
Kekre, N ;
Griffin, C ;
McNulty, J ;
Pandey, S .
CANCER CHEMOTHERAPY AND PHARMACOLOGY, 2005, 56 (01) :29-38
[67]   Bio-guided isolation of cholinesterase inhibitors from the bulbs of Crinum x powellii [J].
Kissling, J ;
Ioset, JR ;
Marston, A ;
Hostettmann, K .
PHYTOTHERAPY RESEARCH, 2005, 19 (11) :984-987
[68]  
Kumemura T, 2005, HETEROCYCLES, V66, P87
[69]  
LAHIRI S, 2006, Patent No. 2006046096
[70]  
LAHIRI S, 2006, Patent No. 20060103546