Amaryllidaceae and Sceletium alkaloids

被引:101
作者
Jin, Zhong [1 ]
机构
[1] Nankai Univ, State Key Lab Elemento Organ Chem, Tianjin 300071, Peoples R China
[2] Nankai Univ, Inst Elemento Organ Chem, Tianjin 300071, Peoples R China
关键词
D O I
10.1039/b502163b
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
A great number of natural products, especially alkaloids, which exhibit a range of biological activities including acetylcholinesterase inhibition and antineoplastic, cardiovascular and immunostimulatory activities, have been isolated from the plants of the Amaryllidaceae family. This review summarizes isolation, biological activity, and synthetic studies of these alkaloids. The primary biosynthetic pathways of each type of alkaloids are also proposed.
引用
收藏
页码:886 / 905
页数:20
相关论文
共 122 条
[1]   New crinine-type alkaloids with inhibitory effect on induction of inducible nitric oxide synthase from Crinum yemense [J].
Abdel-Halim, OB ;
Morikawa, T ;
Ando, S ;
Matsuda, H ;
Yoshikawa, M .
JOURNAL OF NATURAL PRODUCTS, 2004, 67 (07) :1119-1124
[2]  
Abou-Donia AH, 2005, CHROMATOGRAPHIA, V19, P147
[3]  
Aboul-Ela MA, 2004, PHARMAZIE, V59, P894
[4]   Novel routes to pyrroles, indoles and carbazoles -: Applications in natural product synthesis [J].
Agarwal, S ;
Cämmerer, S ;
Filali, S ;
Fröhner, W ;
Knöll, J ;
Krahl, MP ;
Reddy, KR ;
Knölker, HJ .
CURRENT ORGANIC CHEMISTRY, 2005, 9 (15) :1601-1614
[5]   Microwave-enhanced synthesis of N-shifted buflavine analogues via a Suzuki-ring-closing metathesis protocol [J].
Appukkuttan, P ;
Dehaen, W ;
Van der Eycken, E .
ORGANIC LETTERS, 2005, 7 (13) :2723-2726
[6]   Immunostimulatory effect of methanol extract of Curculigo orchioides on immunosuppressed mice [J].
Bafna, AR ;
Mishra, SH .
JOURNAL OF ETHNOPHARMACOLOGY, 2006, 104 (1-2) :1-4
[7]   Drug discovery from medicinal plants [J].
Balunas, MJ ;
Kinghorn, AD .
LIFE SCIENCES, 2005, 78 (05) :431-441
[8]   Model studies toward the synthesis of kirkine [J].
Barclay, GL ;
Quiclet-Sire, B ;
Sanchez-Jimenez, G ;
Zard, SZ .
ORGANIC & BIOMOLECULAR CHEMISTRY, 2005, 3 (05) :823-835
[9]   Synthesis of the alkaloid natural products (+)-plicane and (-)-obliquine, using polymer-supported reagents and scavengers [J].
Baxendale, IR ;
Ley, SV .
INDUSTRIAL & ENGINEERING CHEMISTRY RESEARCH, 2005, 44 (23) :8588-8592
[10]   CGC-MS of alkaloids in Leucojum aestivum plants and their in vitro cultures [J].
Berkov, S ;
Pavlov, A ;
Ilieva, M ;
Burrus, M ;
Popov, S ;
Stanilova, M .
PHYTOCHEMICAL ANALYSIS, 2005, 16 (02) :98-103