The role of volumetric MRI in understanding mild cognitive impairment and similar classifications

被引：42

作者：

Anstey, KJ ^{[1
]}

Maller, JJ ^{[1
]}

机构：

[1] Australian Natl Univ, Mental Hlth Res Ctr, Canberra, ACT 0200, Australia

来源：

AGING & MENTAL HEALTH | 2003年 / 7卷 / 04期

基金：

英国医学研究理事会;

关键词：

D O I：

10.1080/1360786031000120732

中图分类号：

R592 [老年病学]; C [社会科学总论];

学科分类号：

03 ; 0303 ; 100203 ;

摘要：

We review nineteen empirical studies of mild cognitive impairment (MCI), age-associated memory impairment (AAMI) and related classifications reporting volumetric data on the hippocampus, entorhinal cortex and amygdala. Studies varied considerably in terms of the selection of participants, sample characteristics, the definitions of regions of interest and normalization techniques. Effect sizes for differences in left hippocampal volume and right hippocampal volumes of AAMI, MCI and pre-clinical dementia groups compared with controls ranged from 0.47 to 1.34. Effect sizes for left and right hippocampal volumes for Alzheimer's disease (AD) versus control were 1.88 and 1.75 respectively. Longitudinal results confirm that initial hippocampal volume is predictive of conversion to AD. Greater standardization in methodology and the development of normative age-referenced databases of regional brain volumes is required.

引用

页码：238 / 250

页数：13

共 44 条

[1] Ageing of the brain [J].

Anderton, BH .

MECHANISMS OF AGEING AND DEVELOPMENT, 2002, 123 (07) :811-817

[2]

Bozzao A, 2001, AM J NEURORADIOL, V22, P1030

[3] Magnetic resonance measures in Alzheimer disease: Their utility in early diagnosis and evaluating disease progression [J].

Bracco, L ;

Piccini, C ;

Manfredi, G ;

Fonda, C ;

Falcini, M ;

Amaducci, L .

ALZHEIMER DISEASE & ASSOCIATED DISORDERS, 1999, 13 (03) :157-164

[4] The human amygdala: a systematic review and meta-analysis of volumetric magnetic resonance imaging [J].

Brierley, B ;

Shaw, P ;

David, AS .

BRAIN RESEARCH REVIEWS, 2002, 39 (01) :84-105

[5] The effects of age, education, and gender on the Mattis Dementia Rating Scale performance of elderly Chinese and American individuals [J].

Chan, AS ;

Choi, MK ;

Salmon, DP .

JOURNALS OF GERONTOLOGY SERIES B-PSYCHOLOGICAL SCIENCES AND SOCIAL SCIENCES, 2001, 56 (06) :P356-P363

[6] An analysis of systems of classifying mild cognitive impairment in older people [J].

Collie, A ;

Maruff, P .

AUSTRALIAN AND NEW ZEALAND JOURNAL OF PSYCHIATRY, 2002, 36 (01) :133-140

[7] Specific hippocampal volume reductions in individuals at risk for Alzheimer's disease [J].

Convit, A ;

DeLeon, MJ ;

Tarshish, C ;

DeSanti, S ;

Tsui, W ;

Rusinek, H ;

George, A .

NEUROBIOLOGY OF AGING, 1997, 18 (02) :131-138

[8] Age-Associated Memory Impairment: Proposed Diagnostic Criteria and Measures of Clinical Change - Report of a National Institute of Mental Health Work Group [J].

Crook, Thomas ;

Bartus, Raymond T. ;

Ferris, Steven H. ;

Whitehouse, Peter ;

Cohen, Gene D. ;

Gershon, Samuel .

DEVELOPMENTAL NEUROPSYCHOLOGY, 1986, 2 (04) :261-276

[9] Prediction of cognitive decline in normal elderly subjects with 2-[18F]fluoro-2-deoxy-D-glucose/positron-emission tomography (FDG/PET) [J].

de Leon, MJ ;

Convit, A ;

Wolf, OT ;

Tarshish, CY ;

DeSanti, S ;

Rusinek, H ;

Tsui, W ;

Kandil, E ;

Scherer, AJ ;

Roche, A ;

Imossi, A ;

Thorn, E ;

Bobinski, M ;

Caraos, C ;

Lesbre, P ;

Schlyer, D ;

Poirier, J ;

Reisberg, B ;

Fowler, J .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2001, 98 (19) :10966-10971

[10] Hippocampal formation glucose metabolism and volume losses in MCI and AD [J].

De Santi, S ;

de Leon, MJ ;

Rusinek, H ;

Convit, A ;

Tarshish, CY ;

Roche, A ;

Tsui, WH ;

Kandil, E ;

Boppana, M ;

Daisley, K ;

Wang, GJ ;

Schlyer, D ;

Fowler, J .

NEUROBIOLOGY OF AGING, 2001, 22 (04) :529-539

← 1 2 3 4 5 →