Are patients with comorbidities more prone to sequalae in severe COVID-19

被引:0
作者
Daga, Mradul Kumar [1 ]
Mawari, Govind [1 ]
Chand, Siddharth [1 ]
Aarthi, J. [1 ]
Raghu, R. V. [1 ]
Kumar, Naresh [1 ]
机构
[1] Maulana Azad Med Coll, Dept Med, New Delhi 110002, India
关键词
Corticosteroids; COVID-19; sequalae; ACUTE RESPIRATORY SYNDROME; FIBROSIS;
D O I
10.4103/injms.injms_37_21
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Majority hospital admission in COVID-19 is because of pneumonia. Few develop progressive and permanent pulmonary fibrosis. Here, we present three patients of severe COVID-19 pneumonia requiring intensive care unit care. Computed tomography (CT) of the chest of these patients revealed multiple areas of lung involvement at the 4th week of illness. Follow-up CT scan and pulmonary function test were done after 5 months to look for residual changes. Pulmonary fibrosis induced by COVID-19 is being documented. We need long-term follow-up studies to observe the clinical and radiological course of fibrosis. Corticosteroids and antifibrotic agents in such cases are being looked into.
引用
收藏
页码:161 / 164
页数:4
相关论文
共 19 条
[1]   Post COVID-19 fibrosis, an emerging complication of SARS-CoV-2 infection [J].
Alhiyari, Mousa Ahmad ;
Ata, Fateen ;
Alghizzawi, Mohd Islam ;
Bilal, Ammara Bint, I ;
Abdulhadi, Ahmad Salih ;
Yousaf, Zohaib .
IDCASES, 2021, 23
[2]   Clinical Implications of SARS-CoV-2 Interaction With Renin Angiotensin System JACC Review Topic of the Week [J].
Brojakowska, Agnieszka ;
Narula, Jagat ;
Shimony, Rony ;
Bander, Jeffrey .
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, 2020, 75 (24) :3085-3095
[3]   Mechanical Ventilation-associated Lung Fibrosis in Acute Respiratory Distress Syndrome A Significant Contributor to Poor Outcome [J].
Cabrera-Benitez, Nuria E. ;
Laffey, John G. ;
Parotto, Matteo ;
Spieth, Peter M. ;
Villar, Jesus ;
Zhang, Haibo ;
Slutsky, Arthur S. .
ANESTHESIOLOGY, 2014, 121 (01) :189-198
[4]   Antifibrotic therapy for fibrotic lung disease beyond idiopathic pulmonary fibrosis [J].
Collins, Bridget F. ;
Raghu, Ganesh .
EUROPEAN RESPIRATORY REVIEW, 2019, 28 (153)
[5]   COVID-19 and risk of pulmonary fibrosis: the importance of planning ahead [J].
Gentile, Francesco ;
Aimo, Alberto ;
Forfori, Francesco ;
Catapano, Giosue ;
Clemente, Alberto ;
Cademartiri, Filippo ;
Emdin, Michele ;
Giannoni, Alberto .
EUROPEAN JOURNAL OF PREVENTIVE CARDIOLOGY, 2020, 27 (13) :1442-1446
[6]   The 1-year impact of severe acute respiratory syndrome on pulmonary function, exercise capacity, and quality of life in a cohort of survivors [J].
Hui, DS ;
Wong, KT ;
Ko, FW ;
Tam, LS ;
Chan, DP ;
Woo, J ;
Sung, JJY .
CHEST, 2005, 128 (04) :2247-2261
[7]   Overlapping and discrete aspects of the pathology and pathogenesis of the emerging human pathogenic coronaviruses SARS-CoV, MERS-CoV, and 2019-nCoV [J].
Liu, Jia ;
Zheng, Xin ;
Tong, Qiaoxia ;
Li, Wei ;
Wang, Baoju ;
Sutter, Kathrin ;
Trilling, Mirko ;
Lu, Mengji ;
Dittmer, Ulf ;
Yang, Dongliang .
JOURNAL OF MEDICAL VIROLOGY, 2020, 92 (05) :491-494
[8]  
Mineo G, 2012, RADIOL MED, V117, P185, DOI 10.1007/s11547-011-0740-3
[9]   Persistent Post-COVID-19 Interstitial Lung Disease An Observational Study of Corticosteroid Treatment [J].
Myall, Katherine Jane ;
Mukherjee, Bhashkar ;
Castanheira, Ana Margarida ;
Lam, Jodie L. ;
Benedetti, Giulia ;
Mak, Sze Mun ;
Preston, Rebecca ;
Thillai, Muhunthan ;
Dewar, Amy ;
Molyneaux, Philip L. ;
West, Alex G. .
ANNALS OF THE AMERICAN THORACIC SOCIETY, 2021, 18 (05) :799-806
[10]   Intensive care management of coronavirus disease 2019 (COVID-19): challenges and recommendations [J].
Phua, Jason ;
Weng, Li ;
Ling, Lowell ;
Egi, Moritoki ;
Lim, Chae-Man ;
Divatia, Jigeeshu Vasishtha ;
Shrestha, Babu Raja ;
Arabi, Yaseen M. ;
Ng, Jensen ;
Gomersall, Charles D. ;
Nishimura, Masaji ;
Koh, Younsuck ;
Du, Bin .
LANCET RESPIRATORY MEDICINE, 2020, 8 (05) :506-517