Growth Inhibition Study of Urinary Type Brushite Crystal Using Potassium Dihydrogen Citrate Solution

被引：5

作者：

Bhojani, Amit ^{[1
,2
]}

Jethva, Harshkant ^{[1
]}

Joshi, Mihir ^{[1
]}

机构：

[1] Saurashtra Univ, Dept Phys, Rajkot 360005, Gujarat, India

[2] Indrashil Univ, Sch Sci, Rajpur 382740, Kadi, India

来源：

DAE SOLID STATE PHYSICS SYMPOSIUM 2018 | 2019年 / 2115卷

关键词：

PHOSPHATE DIHYDRATE CRYSTALS; CALCIUM-OXALATE;

D O I：

10.1063/1.5113256

中图分类号：

O59 [应用物理学];

学科分类号：

摘要：

Brushite (CaHPO4.2H2O), or Calcium Hydrogen Phosphate Dihydrate (CHPD), crystal is known as Phosphate stone and commonly found in urolithiasis. Brushite is comparatively hard and difficult to remove by shock waves and ultrasonic lithotripsy. The current study is conducted to find out the inhibiting effect of Potassium Dihydrogen Citrate (KDC) solution, on brushite crystals using single-diffusion gel growth technique, at room temperature. Star and needle type crystals are grown in gel medium. As the molar concentration of KDC solution added in the supernatant solution during crystal growth, the average size of grown brushite crystals decreases and for 0.5 M KDC solution, no growth of brushite crystals is observed. The possible mechanism is proposed with the help of Powder XRD, SEM and EDAX analyses. These in-vitro results can help to evaluate the risk factor of brushite crystals.

引用

页数：4

共 20 条

[1]

Amjad Z., 2007, Advances in Crystal Growth Inhibition Technologies

[2]

[Anonymous], 1998, CAMPBELLS UROLOGY

[3]

Basavaraj D.R., 2007, EAU-EBU Update Series, V5, P126, DOI [10.1016/j.eeus.2007.03.002, DOI 10.1016/J.EEUS.2007.03.002]

[4]

Campbell M. F., 2002, CAMPBELLS UROLOGY, V1

[5]

Caudarella R., 2007, ARCH ITAL UROL ANDRO, V81, P182

[6]

Caudarella Renata, 2009, Arch Ital Urol Androl, V81, P182

[7] Rethinking Classical Crystal Growth Models through Molecular Scale Insights: Consequences of Kink-Limited Kinetics [J].

De Yoreo, J. J. ;

Zepeda-Ruiz, L. A. ;

Friddle, R. W. ;

Qiu, S. R. ;

Wasylenki, L. E. ;

Chernov, A. A. ;

Gilmer, G. H. ;

Dove, P. M. .

CRYSTAL GROWTH & DESIGN, 2009, 9 (12) :5135-5144

[8] The mechanisms of crystal growth inhibition by organic and inorganic inhibitors [J].

Dobberschutz, S. ;

Nielsen, M. R. ;

Sand, K. K. ;

Civioc, R. ;

Bovet, N. ;

Stipp, S. L. S. ;

Andersson, M. P. .

NATURE COMMUNICATIONS, 2018, 9

[9]

Joseph K.C., 2017, IOSR J. Pharm. Biol. Sci, V12, P47

[10]

Joseph KC, 2005, CURR SCI INDIA, V88, P1232

← 1 2 →