Hair Growth in a Patient with Alopecia Areata on Tocilizumab

被引:3
作者
Walker, Chloe J. [1 ]
Flanagan, Kelly E. [1 ]
Pathoulas, James T. [1 ]
Pupo Wiss, Isabel [1 ]
Senna, Maryanne M. [1 ]
机构
[1] Harvard Med Sch, Massachusetts Gen Hosp, Dept Dermatol, Boston, MA 02115 USA
来源
SKIN APPENDAGE DISORDERS | 2021年 / 7卷 / 05期
关键词
Alopecia areata; Tocilizumab; Case report; Posterior uveitis; Hair regrowth; INTERLEUKIN-6; IL-6;
D O I
10.1159/000516300
中图分类号
R75 [皮肤病学与性病学];
学科分类号
100206 ;
摘要
Introduction: Tocilizumab (TCZ), a recombinant humanized antihuman monoclonal antibody targeting interleukin-6 (IL-6) signaling, is often utilized in the management of autoimmune disease. Few reports have demonstrated hair growth changes in patients on TCZ. Case Presentation: Herein, we review the literature and report a 21-year-old woman with progressive alopecia areata (AA) presenting with AA improvement while on TCZ for concomitant posterior uveitis. Discussion: Our case demonstrates the potential ability of TCZ to disrupt IL-6 signaling involved in AA, leading to hair loss and regrowth.
引用
收藏
页码:408 / 412
页数:5
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