Imaging of neuroendocrine tumors: A pictorial review of the clinical value of different imaging modalities

被引:6
作者
Pirasteh, Ali [1 ]
Lovrec, Petra [1 ]
Bodei, Lisa [2 ]
机构
[1] Univ Wisconsin, Dept Radiol, Madison, WI 53706 USA
[2] Mem Sloan Kettering Canc Ctr, Mol Imaging & Therapy Serv, Dept Radiol, 1275 York Ave, New York, NY 10021 USA
关键词
Neuroendocrine tumor; Computed tomography; Magnetic resonance imaging; Positron emission tomography; Ultrasound;
D O I
10.1007/s11154-021-09631-7
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Neuroendocrine tumors (NETs) are multifaceted tumors occurring in a variety of organs and often present as metastatic at the time of diagnosis. Accurate staging is the most significant factor in therapy planning, but it remains a challenge. Imaging is established as the cornerstone for disease detection/diagnosis, staging, and follow up. To accurately assess and monitor tumor burden in patients with NETs, various imaging techniques have been developed and optimized. Current recommendations for the imaging of patients with NETs include a combination of both morphologic (or anatomic) and molecular imaging, but a final choice can be puzzling for clinicians. Recognizing that there is no uniform sequence consensus on the "best" imaging test, and the heterogeneity of technologic availability at different centers, we hope to provide a pictorial review of the different imaging techniques and their role and utility in management of patients with NETs, aimed to provide a practical guide for all clinicians.
引用
收藏
页码:539 / 552
页数:14
相关论文
共 114 条
[1]  
Adams S, 1998, EUR J NUCL MED, V25, P79
[2]  
Anderson MA, 2000, AM J GASTROENTEROL, V95, P2271
[3]   The Impact of Somatostatin Receptor-Directed PET/CT on the Management of Patients with Neuroendocrine Tumor: A Systematic Review and Meta-Analysis [J].
Barrio, Martin ;
Czernin, Johannes ;
Fanti, Stefano ;
Ambrosini, Valentina ;
Binse, Ina ;
Du, Lin ;
Eiber, Matthias ;
Herrmann, Ken ;
Fendler, Wolfgang P. .
JOURNAL OF NUCLEAR MEDICINE, 2017, 58 (05) :756-761
[4]   Emerging Applications for Ferumoxytol as a Contrast Agent in MRI [J].
Bashir, Mustafa R. ;
Bhatti, Lubna ;
Marin, Daniele ;
Nelson, Rendon C. .
JOURNAL OF MAGNETIC RESONANCE IMAGING, 2015, 41 (04) :884-898
[5]   Simultaneous 68Ga-DOTATOC PET/MRI in Patients With Gastroenteropancreatic Neuroendocrine Tumors Initial Results [J].
Beiderwellen, Karsten J. ;
Poeppel, Thorsten D. ;
Hartung-Knemeyer, Verena ;
Buchbender, Christian ;
Kuehl, Hilmar ;
Bockisch, Andreas ;
Lauenstein, Thomas C. .
INVESTIGATIVE RADIOLOGY, 2013, 48 (05) :273-279
[6]   Fluorodeoxyglucose positron emission tomography and somatostatin receptor scintigraphy for diagnosing and staging carcinoid tumours: correlations with the pathological indexes p53 and Ki-67 [J].
Belhocine, T ;
Foidart, J ;
Rigo, P ;
Najjar, F ;
Thiry, A ;
Quatresooz, P ;
Hustinx, R .
NUCLEAR MEDICINE COMMUNICATIONS, 2002, 23 (08) :727-734
[7]   Whole-Body 68Ga-DOTANOC PET/MRI Versus 68Ga-DOTANOC PET/CT in Patients With Neuroendocrine Tumors: A Prospective Study in 28 Patients [J].
Berzaczy, Dominik ;
Giraudo, Chiara ;
Haug, Alexander R. ;
Raderer, Markus ;
Senn, Daniela ;
Karanikas, Georgios ;
Weber, Michael ;
Mayerhoefer, Marius E. .
CLINICAL NUCLEAR MEDICINE, 2017, 42 (09) :669-674
[8]   18F-Fluorodeoxyglucose Positron Emission Tomography Predicts Survival of Patients with Neuroendocrine Tumors [J].
Binderup, Tina ;
Knigge, Ulrich ;
Loft, Annika ;
Federspiel, Birgitte ;
Kjaer, Andreas .
CLINICAL CANCER RESEARCH, 2010, 16 (03) :978-985
[9]   PRRT neuroendocrine tumor response monitored using circulating transcript analysis: the NETest [J].
Bodei, Lisa ;
Kidd, Mark S. ;
Singh, Aviral ;
van der Zwan, Wouter A. ;
Severi, Stefano ;
Drozdov, Ignat A. ;
Malczewska, Anna ;
Baum, Richard P. ;
Kwekkeboom, Dik J. ;
Paganelli, Giovanni ;
Krenning, Eric P. ;
Modlin, Irvin M. .
EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING, 2020, 47 (04) :895-906
[10]   The Status of Neuroendocrine Tumor Imaging: From Darkness to Light? [J].
Bodei, Lisa ;
Sundin, Anders ;
Kidd, Mark ;
Prasad, Vikas ;
Modlin, Irvin M. .
NEUROENDOCRINOLOGY, 2015, 101 (01) :1-17