The paper considers the detection of beetle infestations in North American pine forests using high temporal resolution, coarse spatial resolution MODIS remotely sensed satellite images. Two methods are proposed to detect beetle infestation, both applying a triply modulated cosine model. The first method uses an Extended Kalman Filter (EKF) for estimating model parameters, and the second a Least Squares estimator. When beetles infest a forest, the changes in the affect large geographical area. Therefore, the change detection metrics are based on the time series of each pixel, and do not utilize information from neighboring pixels. Using data from the Rocky Mountain region of the United States and of British Columbia in Canada, we show that our methods are highly effective at detecting beetle infestations.