Organic optical agents for image-guided combined cancer therapy

被引：8

作者：

Gao, Zhiyuan ^{[1
,2
,3
]}

Li, Cong ^{[1
]}

Shen, Jing ^{[1
]}

Ding, Dan ^{[1
,2
,3
]}

机构：

[1] Nankai Univ, Affiliated Stomatol Hosp, Tianjin Key Lab Oral & Maxillofacial Funct Recons, Tianjin Stomatol Hosp, Tianjin 300041, Peoples R China

[2] Nankai Univ, Minist Educ, Key Lab Bioact Mat, Tianjin 300071, Peoples R China

[3] Nankai Univ, Coll Life Sci, Tianjin 300071, Peoples R China

来源：

BIOMEDICAL MATERIALS | 2021年 / 16卷 / 04期

基金：

国家重点研发计划; 中国国家自然科学基金;

关键词：

organic optical agent; combined cancer therapy; phototherapy; chemotherapy; immunotherapy; aggregation-induced emission; PHOTODYNAMIC THERAPY; NANOPARTICLES; RESISTANCE; POLYMER; PHOTOTHERAPY; MECHANISMS; TUMORS;

D O I：

10.1088/1748-605X/abf980

中图分类号：

R318 [生物医学工程];

学科分类号：

0831 ;

摘要：

As a promising non-invasive treatment method, phototherapy has attracted extensive attention in the field of combined cancer therapy. Among various optical agents, organic ones have been considered as a promising clinical phototheranostic agent due to its high safety and non-toxic property. In addition, due to the clear structure, facile processability, organic optical agents can be easily endowed with multiple imaging and phototherapeutic functions, significantly simplifying the relatively complex system of imaging-guided combined cancer therapy. This review summarizes the recent research on organic optical agents in imaging-guided combined cancer therapy. The application of organic optical agents in a variety of combined cancer therapeutic modes guided by imaging are introduced respectively, including photodynamic and photothermal combined therapy, phototherapy-combined cancer chemotherapy, and phototherapy-combined cancer immunotherapy. Finally, the concluding remarks and the future prospects are discussed.

引用

页数：12

共 83 条

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