2021 update of the AGIHO guideline on evidence-based management of COVID-19 in patients with cancer regarding diagnostics, viral shedding, vaccination and therapy

被引：37

作者：

Giesen, Nicola ^{[1
]}

Sprute, Rosanne ^{[2
,3
,4
]}

Ruethrich, Maria ^{[5
,6
]}

Khodamoradi, Yascha ^{[7
]}

Mellinghoff, Sibylle C. ^{[2
,3
,4
,20
]}

Beutel, Gernot ^{[8
,9
]}

Lueck, Catherina ^{[8
,9
]}

Koldehoff, Michael ^{[9
,10
]}

Hentrich, Marcus ^{[11
]}

Sandherr, Michael ^{[12
]}

von Bergwelt-Baildon, Michael ^{[9
,13
]}

Wolf, Hans-Heinrich ^{[14
]}

Hirsch, Hans H. ^{[15
,16
,17
]}

Wormann, Bernhard ^{[18
]}

Cornely, Oliver A. ^{[2
,3
,4
]}

Koehler, Philipp ^{[2
,3
,4
]}

Schalk, Enrico ^{[9
,19
]}

von Lilienfeld-Toal, Marie ^{[5
,6
]}

机构：

[1] Univ Hosp Heidelberg, Dept Haematol & Oncol, Internal Med 5, Neuenheimer Feld 410, D-69120 Heidelberg, Germany

[2] Univ Cologne, Fac Med, Partner Site Bonn Cologne, Cologne, Germany

[3] Univ Hosp Cologne, Dept Internal Med 1, Excellence Ctr Med Mycol ECMM, Ctr Integrated Oncol CIO ABCD,German Ctr Infect R, Partner Site Bonn Cologne, Cologne, Germany

[4] Univ Cologne, Cologne Excellence Cluster Cellular Stress Respon, Cologne, Germany

[5] Univ Hosp Jena, Dept Haematol & Med Oncol, Clin Internal Med 2, Jena, Germany

[6] Leibniz Inst Nat Prod Res & Infect Biol, Hans Knoll Inst, Jena, Germany

[7] Goethe Univ Frankfurt, Dept Internal Med, Infect Dis, Frankfurt, Germany

[8] Hannover Med Sch, Dept Haematol Haemostasis Oncol & Stem Cell Trans, Hannover, Germany

[9] German Soc Haematol & Med Oncol DGHO, Working Party Intens Care Haematol & Oncol Patien, Cologne, Germany

[10] Univ Duisburg Essen, Univ Hosp Essen, West German Canc Ctr, Dept Bone Marrow Transplantat, Essen, Germany

[11] Red Cross Hosp, Dept Med Haematol Oncol 3, Munich, Germany

[12] Med Care Ctr Penzberg, Specialist Clin Haematol & Oncol, Penzberg, Germany

[13] LMU Univ Hosp, CCC Munich, Dept Internal Med 3, DKTK Partner Site Munich,BZKF Partner Site Munich, Munich, Germany

[14] Sudharzklinikum, Dept Haematol Oncol & Haemostaseol, Internal Med 3, Nordhausen, Germany

[15] Univ Basel, Transplantat & Clin Virol, Dept Biomed, Haus Peterspl, Basel, Switzerland

[16] Univ Hosp Basel, Lab Med, Clin Virol, Basel, Switzerland

[17] Univ Hosp Basel, Infect Dis & Hosp Epidemiol, Basel, Switzerland

[18] Charite Univ Med Berlin, Dept Med, Div Haematol Oncol & Tumour Immunol, Berlin, Germany

[19] Otto von Guericke Univ, Med Ctr, Dept Haematol & Oncol, Magdeburg, Germany

[20] Univ Med Ctr Hamburg Eppendorf, Dept Med 1, Div Infect Dis, Hamburg, Germany

来源：

EUROPEAN JOURNAL OF CANCER | 2021年 / 147卷

关键词：

COVID-19; SARS-CoV-2; Cancer; Haematological malignancy; Vaccination; Guideline; DISEASES WORKING PARTY; LYMPHOMA PATIENTS; INFLUENZA VACCINATION; GERMAN SOCIETY; INFECTIONS; SARS-COV-2; RITUXIMAB; MALIGNANCIES; HEMATOLOGY;

D O I：

10.1016/j.ejca.2021.01.033

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

The worldwide spread of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and the associated infectious coronavirus disease (COVID-19) has posed a unique challenge to medical staff, patients and their families. Patients with cancer, particularly those with haematologic malignancies, have been identified to be at high risk to develop severe COVID-19. Since publication of our previous guideline on evidence-based management of COVID-19 in patients with cancer, research efforts have continued and new relevant data has come to light, maybe most importantly in the field of vaccination studies. Therefore, an update of our guideline on several clinically important topics is warranted. Here, we provide a concise update of evidence-based recommendations for rapid diagnostics, viral shedding, vaccination and therapy of COVID-19 in patients with cancer. This guideline update was prepared by the Infectious Diseases Working Party (AGIHO) of the German Society for Haematology and Medical Oncology by critically reviewing the currently available data on these topics applying evidence-based medicine criteria. (C) 2021 The Author(s). Published by Elsevier Ltd.

引用

页码：154 / 160

页数：7

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