A green synthesis in water of novel (1,5,3-dithiazepan-3-yl)alkanoic acids by the multicomponent reaction of amino acids, O, and 1,2-ethanedithiol

被引：0

作者：

Khabibullina, Guzel R. ^{[1
]}

Fedotova, Ekaterina S. ^{[1
]}

Akhmetova, Vnira R. ^{[1
]}

Mesheryakova, Ekaterina S. ^{[1
]}

Khalilov, Leonard M. ^{[1
]}

Ibragimov, Askhat G. ^{[1
]}

机构：

[1] Russian Acad Sci, Inst Petrochem & Catalysis, 141 Prospekt Oktyabrya, Ufa 450075, Russia

来源：

MOLECULAR DIVERSITY | 2016年 / 20卷 / 02期

基金：

俄罗斯基础研究基金会;

关键词：

Multicomponent reaction; MRCs; Amino acids; (1,5,3-Dithiazepan-3-yl)alkanoic acids; Water; Green synthesis; ONE-POT SYNTHESIS; FUNGICIDAL ACTIVITY; ORGANIC-SYNTHESIS; DERIVATIVES; BIS-1,5,3-DITHIAZEPANES; HETEROCYCLES; FORMALDEHYDE; CATALYSTS;

D O I：

10.1007/s11030-016-9656-0

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

A library of new (1,5,3-dithiazepan-3-yl)alkanoic acids was prepared by the multicomponent cyclocondensation of amino acids, formaldehyde, and 1,2-ethanedithiol in water at room temperature for 1 to 5 h in high yields. This green procedure offers several advantages such as an operational simplicity, no catalyst, and no production of hazardous materials.

引用

页码：557 / 565

页数：9

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