Surgical Option for Intestinal Gastrointestinal Stromal Tumors - Perioperative and Oncological Outcomes of Laparoscopic Surgery

Background/Aim: Laparoscopic surgery (LS) is being adopted for gastrointestinal stromal tumors (GISTs) of the stomach. Few studies have examined the outcome of LS for intestinal GISTs. In the present study, we evaluated the outcomes of LS for intestinal GISTs. Patients and Methods: This study was a prospective-collecting retrospective review of 85 patients with intestinal GISTs who underwent LS or laparotomy in 102 months. The demographic data and oncological outcomes were compared. Results: The cohort included 85 patients (26 LS and 59 laparotomy patients). The LS group presented earlier oral resumption and a shorter hospital stay. The recurrence rate, recurrence-free and overall survival were comparable. Tumor size greater than 7 cm [ risk ratio (RR)=4.148; p=0.022] and mitotic index of greater than 5/50 high-power fields (RR=5.500; p=0.002) were two predictors for tumor recurrence. Conclusion: The study demonstrated that LS for intestinal GISTs leads to oncological outcomes comparable to those of laparotomy. Moreover, LS was associated with favorable perioperative recovery and a shorter hospital stay. With strict precautions, LS is a safe and effective procedure for intestinal GISTs.