Substrates for growth cone guidance in brain: Guidance cues for neural connections

被引:1
作者
Torimitsu, K [1 ]
机构
[1] NTT, Basic Res Labs, Kanagawa 24301, Japan
来源
POROUS MATERIALS FOR TISSUE ENGINEERING | 1997年 / 250卷
关键词
growth cone; neurite; axon; NGF; laminin; CAM; chemoattractant; guidance; guiding substrates; patterned substrates;
D O I
10.4028/www.scientific.net/MSF.250.69
中图分类号
T [工业技术];
学科分类号
08 ;
摘要
Neurons extend their neurites to a target during neural development in the brain. During this process, guiding substrates play an important role in guiding the growth cones, the tip of the axons/neurites, precisely to their specific targets. This guidance result in the establishment of a neural circuit in the brain. In this review, I will describe the substrates which may guide the growth cone of the axons/neurites to their targets thus forming synaptic neural connections, and also discuss the mechanisms of this neuronal guidance.
引用
收藏
页码:69 / 88
页数:20
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