Exclusion of active Mycobacterium tuberculosis complex infection with the T-SPOT™.TB assay

被引:16
作者
van Leeuwen, R. M. L.
Bossink, A. W. J.
Thijsen, S. F. T.
机构
[1] Diakonessen Hosp, Dept Internal Med, Utrecht, Netherlands
[2] Diakonessen Hosp, Dept Pulmonol, Utrecht, Netherlands
[3] Diakonessen Hosp, Dept Microbiol & Immunol, Utrecht, Netherlands
关键词
ELISPOT assay; interferon-gamma-releasing assay; nontuberculous mycobacteria; tuberculin skin test; tuberculosis;
D O I
10.1183/09031936.00066506
中图分类号
R56 [呼吸系及胸部疾病];
学科分类号
摘要
The present brief report describes four cases with mycobacterial infection and negative T-SPOT (TM). TB tests. This test proved to be a useful tool to help rule out the diagnosis of active Mycobacterium tuberculosis infection and could therefore prevent unnecessary or inappropriate therapy.
引用
收藏
页码:605 / 607
页数:3
相关论文
共 13 条
[1]   Tuberculin skin testing and in vitro T cell responses to ESAT-6 and culture filtrate protein 10 after infection with Mycobacterium marinum or M-kansasii [J].
Arend, SM ;
van Meijgaarden, KE ;
de Boer, K ;
de Palou, EC ;
van Soolingen, D ;
Ottenhoff, THM ;
van Dissel, JT .
JOURNAL OF INFECTIOUS DISEASES, 2002, 186 (12) :1797-1807
[2]   Tuberculosis elimination in the Netherlands [J].
Borgdorff, MW ;
van der Werf, MJ ;
de Haas, PEW ;
Kremer, K ;
van Soolingen, D .
EMERGING INFECTIOUS DISEASES, 2005, 11 (04) :597-602
[3]   Rapid detection of active and latent tuberculosis infection in HIV-positive individuals by enumeration of Mycobacterium tuberculosis-specific T cells [J].
Chapman, ALN ;
Munkanta, M ;
Wilkinson, KA ;
Pathan, AA ;
Ewer, K ;
Ayles, H ;
Reece, WH ;
Mwinga, A ;
Godfrey-Faussett, P ;
Lalvani, A .
AIDS, 2002, 16 (17) :2285-2293
[4]   Global burden of tuberculosis - Estimated incidence, prevalence, and mortality by country [J].
Dye, C ;
Scheele, S ;
Dolin, P ;
Pathania, V ;
Raviglione, RC .
JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 1999, 282 (07) :677-686
[5]   Use in routine clinical practice of two commercial blood tests for diagnosis of infection with Mycobacterium tuberculosis:: a prospective study [J].
Ferrara, G ;
Losi, M ;
D'Amico, R ;
Roversi, P ;
Piro, R ;
Meacci, M ;
Meccugni, B ;
Dori, IM ;
Andreani, A ;
Bergamini, BM ;
Mussini, C ;
Rumpianesi, F ;
Fabbri, LM ;
Richeldi, L .
LANCET, 2006, 367 (9519) :1328-1334
[6]   AVOIDING FALSE POSITIVES WITH PCR [J].
KWOK, S ;
HIGUCHI, R .
NATURE, 1989, 339 (6221) :237-238
[7]   Rapid detection of Mycobacterium tuberculosis infection by enumeration of antigen-specific T cells [J].
Lalvani, A ;
Pathan, AA ;
McShane, H ;
Wilkinson, RJ ;
Latif, M ;
Conlon, CP ;
Pasvol, G ;
Hill, AVS .
AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 2001, 163 (04) :824-828
[8]   Enhanced contact tracing and spatial tracking of Mycobacterium tuberculosis infection by enumeration of antigen-specific T cells [J].
Lalvani, A ;
Pathan, AA ;
Durkan, H ;
Wilkinson, KA ;
Whelan, A ;
Deeks, JJ ;
Reece, WHH ;
Latif, M ;
Pasvol, G ;
Hill, AVS .
LANCET, 2001, 357 (9273) :2017-2021
[9]   Pyrazinamide and rifampin vs isoniazid for the treatment of latent tuberculosis - Improved completion rates but more hepatotoxicity [J].
McNeill, L ;
Allen, M ;
Estrada, C ;
Cook, P .
CHEST, 2003, 123 (01) :102-106
[10]   Sensitivity of a new commercial enzyme-linked immunospot assay (T SPOT-TB) for diagnosis of tuberculosis in clinical practice [J].
Meier, T ;
Eulenbruch, HP ;
Wrighton-Smith, P ;
Enders, G ;
Regnath, T .
EUROPEAN JOURNAL OF CLINICAL MICROBIOLOGY & INFECTIOUS DISEASES, 2005, 24 (08) :529-536