Anxiety disorders in people with epilepsy

被引：63

作者：

Brandt, Christian ^{[1
]}

Mula, Marco ^{[2
,3
]}

机构：

[1] Mara Hosp, Dept Gen Epileptol, Bethel Epilepsy Ctr, Maraweg 21, D-33617 Bielefeld, Germany

[2] St Georges Univ Hosp NHS Fdn Trust, Atkinson Morley Reg Neurosci Ctr, London, England

[3] St Georges Univ London, Inst Med & Biomed Sci, London, England

来源：

EPILEPSY & BEHAVIOR | 2016年 / 59卷

关键词：

Comorbidity; Prevalence; Diagnosis; Treatment; Quality of life; TEMPORAL-LOBE EPILEPSY; QUALITY-OF-LIFE; OBSESSIVE-COMPULSIVE SYMPTOMS; PSYCHIATRIC COMORBIDITY; ICTAL FEAR; GENERALIZED EPILEPSY; ANTIEPILEPTIC DRUGS; RESECTIVE SURGERY; PILOCARPINE MODEL; RAPID DETECTION;

D O I：

10.1016/j.yebeh.2016.03.020

中图分类号：

B84 [心理学]; C [社会科学总论]; Q98 [人类学];

学科分类号：

03 ; 0303 ; 030303 ; 04 ; 0402 ;

摘要：

Anxiety disorders are frequent, though probably underdiagnosed, comorbidities in epilepsy. Epilepsy and anxiety may share common neurobiological correlates as shown in animal models and suggested by studies demonstrating anxiety disorders before the manifestation of epilepsy. Comorbid anxiety disorders have a major impact on the affected patients' quality of life and may increase the risk for suicidality. Successful treatment of the epilepsy may alleviate anxiety symptoms. Treatment of anxiety is based on selective serotonin reuptake inhibitors, benzodiazepines (although only as second-line choices), and psychotherapy. Specific AEDs (especially pregabalin) have been shown to have anxiolytic properties. This paper is aimed at reviewing anxiety disorders in patients with epilepsy discussing current scientific evidence about pathophysiology, clinical aspects, and treatment strategies. (C) 2016 Elsevier Inc. All rights reserved.

引用

页码：87 / 91

页数：5

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