Reactive oxygen species scavenging activities and inhibition on DNA oxidative damage of dimeric compounds from the oxidation of (-)-epigallocatechin-3-O-gallate

被引：13
作者：
Qi, Xiangyang [1 ,2 ]
机构：
[1] Zhejiang Wah College, Coll Biol Environm Sci, Ningbo 315100, Zhejiang, Peoples R China
[2] Huazhong Agr Univ, Dept Food Sci & Technol, Wuhan 430070, Peoples R China
来源：
FITOTERAPIA | 2010年 / 81卷 / 03期
关键词：
Tea; Dehydrotheasinensin A; Theacitrin C; Antioxidant activity; Chemiluminescence; BLACK TEA; GREEN TEA; ANTIOXIDANT ACTIVITY; CHEMICAL OXIDATION; FREE-RADICALS; GALLATE; ABILITIES; CATECHINS; EPICATECHIN; PRODUCTS;
D O I：
10.1016/j.fitote.2009.09.004
中图分类号：
R914 [药物化学];
学科分类号：
100701 ;
摘要：
The dimeric catechins dehydrotheasinensin A (2) and theacitrin C (3) were prepared from the oxidation of (-)-epigallocatechin-3-O-gallate (EGCG, 1), and their antioxidant activity was investigated using a chemiluminescence (CL) method in vitro Both compounds showed significant inhibitory effects on reactive oxygen species (O-2(-), H2O2 and center dot OH) and DNA oxidative damage, with 2 being more potent than 3 and EGCG itself. (C) 2009 Elsevier B V All rights reserved
引用
收藏
页码：205 / 209
页数：5
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