Zr-mediated synthesis of chiral cyclic imines and their application in Betti reactions

被引：11

作者：

Speich, Elena ^{[1
]}

Banfi, Luca ^{[1
]}

Moni, Lisa ^{[1
]}

Riva, Renata ^{[1
]}

Rocca, Valeria ^{[1
]}

Basso, Andrea ^{[1
]}

机构：

[1] Univ Genoa, Dipartimento Chim & Chim Ind, 31 Via Dodecaneso, I-16146 Genoa, Italy

来源：

CHEMISTRY OF HETEROCYCLIC COMPOUNDS | 2018年 / 54卷 / 03期

关键词：

cyclic imines; Schwartz reagent; Betti reaction; STEREOSELECTIVE SYNTHESIS; SOLVATING AGENTS; AMINONAPHTHOLS; PYRROLIDINES; ALKYLATION; REDUCTION; SECONDARY; ACIDS; BASE;

D O I：

10.1007/s10593-018-2268-0

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A novel synthetic strategy has been outlined to assemble enantiomerically pure Betti bases with unprecedented structures. This involves the Zr-mediated reduction of pyrrolidin-2-ones to cyclic imines and their subsequent reaction with phenolic derivatives.

引用

页码：329 / 333

页数：5

共 32 条

[31] trans-2-Tritylcyclohexanol as a Chiral Auxiliary in Permanganate-Mediated Oxidative Cyclization of 2-Methylenehept-5-enoates: Application to the Synthesis of trans-(+)-Linalool Oxide
Al Hazmi, Ali M.
Sheikh, Nadeem S.
Bataille, Carole J. R.
Al-Hadedi, Azzam A. M.
Watkin, Sam V.
Luker, Tim J.
Camp, Nicholas P.
Brown, Richard C. D.
ORGANIC LETTERS, 2014, 16 (19) : 5104 - 5107
[32] Synthesis of novel planar chiral Ag and Rh N-heterocyclic carbene complexes derived from [2.2]paracyclophane and their application in ultrasound assisted asymmetric addition reactions of organoboronic acids to aldehydes
Duan, Wenzeng
Ma, Yudao
He, Fuyan
Zhao, Lei
Chen, Jianqiang
Song, Chun
TETRAHEDRON-ASYMMETRY, 2013, 24 (5-6) : 241 - 248

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