Zr-mediated synthesis of chiral cyclic imines and their application in Betti reactions

被引：11
|
作者：
Speich, Elena [1 ]
Banfi, Luca [1 ]
Moni, Lisa [1 ]
Riva, Renata [1 ]
Rocca, Valeria [1 ]
Basso, Andrea [1 ]
机构：
[1] Univ Genoa, Dipartimento Chim & Chim Ind, 31 Via Dodecaneso, I-16146 Genoa, Italy
来源：
CHEMISTRY OF HETEROCYCLIC COMPOUNDS | 2018年 / 54卷 / 03期
关键词：
cyclic imines; Schwartz reagent; Betti reaction; STEREOSELECTIVE SYNTHESIS; SOLVATING AGENTS; AMINONAPHTHOLS; PYRROLIDINES; ALKYLATION; REDUCTION; SECONDARY; ACIDS; BASE;
D O I：
10.1007/s10593-018-2268-0
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
A novel synthetic strategy has been outlined to assemble enantiomerically pure Betti bases with unprecedented structures. This involves the Zr-mediated reduction of pyrrolidin-2-ones to cyclic imines and their subsequent reaction with phenolic derivatives.
引用
收藏
页码：329 / 333
页数：5
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