Non-pharmacological management of a hemodynamically significant patent ductus arteriosus

被引:20
作者
Smith, A. [1 ]
McNamara, P. J. [2 ,3 ]
El-Khuffash, A. F. [1 ,4 ]
机构
[1] Rotunda Hosp, Dept Neonatol, Parnell Sq, Dublin 1, Ireland
[2] Univ Toronto, Dept Paediat, Toronto, ON, Canada
[3] Hosp Sick Children, Res Inst, Physiol & Expt Med Program, Toronto, ON, Canada
[4] Royal Coll Surgeons Ireland, Sch Med, Dept Paediat, Dublin, Ireland
关键词
Patent ductus arteriosus; Management; BIRTH-WEIGHT INFANTS; PRETERM INFANTS; CARBON-DIOXIDE; CONSERVATIVE TREATMENT; PREMATURE-INFANTS; INDOMETHACIN; OXYGEN; CLOSURE; TRIAL; FUROSEMIDE;
D O I
10.1016/j.siny.2018.03.008
中图分类号
R72 [儿科学];
学科分类号
100202 ;
摘要
The association between the patent ductus arteriosus (PDA) and neonatal morbidity, mortality and poor neurodevelopmental outcome in later childhood has been the focus of intense debate for decades. The lack of evidence supporting therapeutic strategies aimed at achieving PDA closure has led to the widespread adoption of conservative management aimed at mitigating the impact of shunt volume without achieving ductal closure. In this article, we review this management approach, describe the supportive evidence and potential complications associated with this strategy.
引用
收藏
页码:245 / 249
页数:5
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