Management of Nail Unit Melanoma

被引：15

作者：

Zhang, Junqian ^{[1
]}

Yun, Sook Jung ^{[2
]}

McMurray, Stacy L. ^{[3
]}

Miller, Christopher J. ^{[3
]}

机构：

[1] Univ Penn Hlth Syst, Dept Dermatol, 3600 Spruce St,2 Maloney Bldg, Philadelphia, PA 19104 USA

[2] Chonnam Natl Univ, Dept Dermatol, Med Sch, 160 Baekseo Ro, Gwangju 61469, South Korea

[3] Univ Penn Hlth Syst, Penn Dermatol Oncol Ctr, 3400 Civ Ctr Blvd,Suite 1-3305, Philadelphia, PA 19104 USA

来源：

DERMATOLOGIC CLINICS | 2021年 / 39卷 / 02期

关键词：

Melanoma; Nail unit; Amputation; Functional surgery; Mohs micrographic surgery;

D O I：

10.1016/j.det.2020.12.006

中图分类号：

R75 [皮肤病学与性病学];

学科分类号：

100206 ;

摘要：

Fig. 1. Biopsy findings of early nail unit melanoma with Hutchinson sign. (A) A 62-year-old woman presented with irregular black to brownish longitudinal melanonychia with pigment extending to the hyponychium (Hutchinson nail sign). (8) A 6-mm punch biopsy shows the proximal nail fold and cuticle (blue arrow), the nail plate (green arrow), and nail matrix (red arrow) (hematoxylin and eosin [H&E], original magnification x20). The yellow box indicates the window for higher magnification photomicrographs in C and D. (C) Histopathologic findings are subtle, showing only increased pigmentation and melanocytes (H&E, original magnification x100). (D) Melan-A highlights continuous proliferation of melanocytes with prominent dendrites and pagetoid scatter

引用

页码：269 / 280

页数：12

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