B cells and antibodies in CNS demyelinating disease

被引：180

作者：

Cross, AH ^{[1
]}

Trotter, JL ^{[1
]}

Lyons, JA ^{[1
]}

机构：

[1] Washington Univ, Sch Med, Dept Neurol & Neurosurg, St Louis, MO 63110 USA

来源：

JOURNAL OF NEUROIMMUNOLOGY | 2001年 / 112卷 / 1-2期

关键词：

multiple sclerosis; experimental autoimmune encephalomyelitis; B cell; plasma cell; antibody;

D O I：

10.1016/S0165-5728(00)00409-4

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

There is much evidence to implicate B cells, plasma cells, and their products in the pathogenesis of MS. Despite unequivocal evidence that the animal model for MS, EAE, is initiated by myelin-specific T cells, there is accumulating evidence of a role for B cells, plasma cells, and their products in EAE pathogenesis. The role(s) played by B cells, plasma cells, and antibodies in CNS inflammatory demyelinating diseases are likely to be multifactorial and complex, involving distinct and perhaps opposing roles for B cells versus antibody. (C) 2001 Elsevier Science B.V. All rights reserved.

引用

页码：1 / 14

页数：14

共 50 条

[41] A case of Fabry disease with central nervous system (CNS) demyelinating lesions: a double trouble? [J].

Invernizzi, P. ;

Bonometti, M. A. ;

Turri, E. ;

Benedetti, M. D. ;

Salviati, A. .

MULTIPLE SCLEROSIS JOURNAL, 2008, 14 (07) :1003-1006

[42] CNS Expression of B7-H1 Regulates Pro-Inflammatory Cytokine Production and Alters Severity of Theiler's Virus-Induced Demyelinating Disease [J].

Duncan, D'Anne S. ;

Miller, Stephen D. .

PLOS ONE, 2011, 6 (04)

[43] The pathological spectrum of CNS inflammatory demyelinating diseases [J].

Hu, Wei ;

Lucchinetti, Claudia F. .

SEMINARS IN IMMUNOPATHOLOGY, 2009, 31 (04) :439-453

[44] The pathological spectrum of CNS inflammatory demyelinating diseases [J].

Wei Hu ;

Claudia F. Lucchinetti .

Seminars in Immunopathology, 2009, 31 :439-453

[45] INFLAMMATORY MEDIATORS IN DEMYELINATING DISORDERS OF THE CNS AND PNS [J].

HARTUNG, HP ;

JUNG, SF ;

STOLL, G ;

ZIELASEK, J ;

SCHMIDT, B ;

ARCHELOS, JJ ;

TOYKA, KV .

JOURNAL OF NEUROIMMUNOLOGY, 1992, 40 (2-3) :197-210

[46] Deciphering the Footprints of Autoimmunity in CNS Demyelinating Disorders [J].

Netravathi, M. .

ANNALS OF INDIAN ACADEMY OF NEUROLOGY, 2022, 25 (05) :787-789

[47] Regulatory B Cells and Its Role in Central Nervous System Inflammatory Demyelinating Diseases [J].

Zhou, Ran ;

Luo, Yue-Bei ;

Zeng, Qiu-Ming ;

Yang, Huan .

FRONTIERS IN IMMUNOLOGY, 2020, 11

[48] MRI features and anti-AQP4 antibody status in Idiopathic inflammatory demyelinating CNS disease (IIDCD) in Thai patients [J].

Prayoonwiwat, Naraporn ;

Chawalparit, Orasa ;

Pienpuck, Waraporn ;

Ngamsombat, Chanon ;

Wongsripuemtet, Jitsupa ;

Siritho, Sasitorn .

NEUROLOGY ASIA, 2013, 18 (01) :73-81

[49] SIRT1 Activating compounds reduce oxidative stress mediated neuronal loss in viral induced CNS demyelinating disease [J].

Khan, Reas S. ;

Dine, Kimberly ;

Das Sarma, Jayasri ;

Shindler, Kenneth S. .

ACTA NEUROPATHOLOGICA COMMUNICATIONS, 2014, 2

[50] Modeling compartmentalized chronic immune-mediated demyelinating CNS disease in the Biozzi ABH mouse [J].

Nishri, Yossi ;

Fainstein, Nina ;

Goldfarb, Smadar ;

Hampton, David ;

Macrini, Caterina ;

Meinl, Edgar ;

Chandran, Siddharthan ;

Ben-Hur, Tamir .

JOURNAL OF NEUROIMMUNOLOGY, 2021, 356

← 1 2 3 4 5 →