Menopausal Hormone Treatment in Postmenopausal Women: Risks and Benefits

被引：5

作者：

Dous, George V. ^{[1
]}

Grodman, Richard ^{[1
]}

Mornan, Adenieki ^{[1
]}

Otterbeck, Philip ^{[1
]}

Grigos, Angela ^{[1
]}

机构：

[1] Univ Richmond, Med Ctr, Dept Med Cardiol & Endocrinol, Staten Isl, NY 10314 USA

来源：

SOUTHERN MEDICAL JOURNAL | 2014年 / 107卷 / 11期

关键词：

coronary artery disease; estrogen; postmenopausal; progesterone; CARDIOVASCULAR-DISEASE PREVENTION; CORONARY-ARTERY ATHEROSCLEROSIS; ESTROGEN REPLACEMENT; NITRIC-OXIDE; HEALTH OUTCOMES; THERAPY; PROGESTERONE; ESTRADIOL; HEART; PROGRESSION;

D O I：

10.14423/SMJ.0000000000000192

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Our objectives in this review were to examine the relevant menopausal hormone treatment (MHT) trials in postmenopausal women during the past 3 decades, provide an insight analysis of these studies from a clinical point of view, determine the efficacy and applicability of hormone therapy in the prevention of cardiovascular diseases, and provide suggestions on the use of MHT as a cardiovascular disease prophylaxis based on the available data. MHT may have a more complicated role in cardiovascular protection, and there is a need for further research to elucidate the dose and type of estrogen, its route of administration, the time of MHT initiation, and the preventive role of MHT in women's health.

引用

页码：689 / 695

页数：7

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