Efficacy of neck circumference to identify metabolic syndrome in 3-10 year-old European children: Results from IDEFICS study

被引：13
作者：
Formisano, A. [1 ]
Bammann, K. [2 ,3 ]
Fraterman, A. [4 ]
Hadjigeorgiou, C. [5 ]
Herrmann, D. [3 ]
Iacoviello, L.
Marild, S. [7 ]
Moreno, L. A. [6 ,8 ]
Nagy, P. [9 ]
Van Den Bussche, K. [10 ]
Veidebaum, T. [11 ]
Lauria, F. [1 ]
Siani, A. [1 ]
机构：
[1] CNR, Inst Food Sci, Epidemiol & Populat Genet, Via Roma 64, I-83100 Avellino, Italy
[2] Univ Bremen, Inst Publ Hlth & Nursing Sci, D-28359 Bremen, Germany
[3] Leibniz Inst Prevent Res & Epidemiol BIPS GmbH, Bremen, Germany
[4] Lab Med Dortmund, Eberhard & Partner, Dortmund, Germany
[5] Child Hlth Res & Educ Inst, Strovolos, Cyprus
[6] IRCCS Mediterranean Neurol Inst Neuromed, Dept Epidemiol & Prevent, Lab Mol & Nutr Epidemiol, Pozzilli, Italy
[7] Univ Gothenburg, Queen Silvia Childrens Hosp, Dept Pediat, Gothenburg, Sweden
[8] Univ Zaragoza, Growth Exercise Nutr & Dev GENUD Res Grp, Zaragoza, Spain
[9] Univ Pecs, Dept Pediat, Pecs, Hungary
[10] Univ Ghent, Dept Publ Hlth, B-9000 Ghent, Belgium
[11] Natl Inst Hlth Dev, Tallinn, Estonia
来源：
NUTRITION METABOLISM AND CARDIOVASCULAR DISEASES | 2016年 / 26卷 / 06期
关键词：
Neck circumference; Metabolic syndrome; Upper-body fat; ROC curve; Children; CARDIOVASCULAR RISK-FACTORS; 3RD NATIONAL-HEALTH; INSULIN-RESISTANCE; BODY-COMPOSITION; REFERENCE VALUES; YOUNG-CHILDREN; ASSOCIATION; PERCENTILES; OVERWEIGHT; AMERICAN;
D O I：
10.1016/j.numecd.2016.02.012
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
Background and aims: Several studies demonstrated that larger neck circumference (NC) in children and adolescents may help to identify obesity and cardio-metabolic abnormalities. We aimed to evaluate the correlation between NC and metabolic syndrome (MetS) risk factors and to determine the utility of this anthropometric index to identify MetS in European children. Methods and results: The present cross-sectional analysis includes 15,673 children (3-10 years) participating in the IDEFICS study. A continuous MetS (cMetS) score was calculated summing age and sex standardized z-scores of specific MetS risk factors. Receiver Operating Characteristic analysis, stratified by one-year age groups, was used to determine the ability of NC to identify children with unfavorable metabolic profile, corresponding to cMetS score >= 90th percentile. The areas under the curve values for NC associated with cMetS score values >= 90th percentile were significantly greater in girls than in boys (p < 0.001), except for 5 < 6 years group. For boys, optimal NC cut-off values ranged from 26.2 cm for the lowest age group (3 < 4 years), up to 30.9 cm for the highest age group (9 < 10 years). In girls, corresponding values varied from 24.9 cm to 29.6 cm. Conclusion: The study demonstrated the efficacy of NC in identifying European children with an unfavorable metabolic profile. (C) 2016 The Italian Society of Diabetology, the Italian Society for the Study of Atherosclerosis, the Italian Society of Human Nutrition, and the Department of Clinical Medicine and Surgery, Federico II University. Published by Elsevier B.V. All rights reserved.
引用
收藏
页码：510 / 516
页数：7
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