Development of optical fibre sensors for Online pH monitoring in microbioreactors

被引：0

作者：

Wu, Min-Hsien ^{[1
]}

Wang, Junbo ^{[2
]}

Lin, Jr-Lung ^{[3
]}

Cui, Zhanfeng ^{[4
]}

Cui, Zheng ^{[1
]}

机构：

[1] Rutherford Appleton Lab, Oxford, England

[2] Inst Elect, Beijing, Peoples R China

[3] I Shou Univ, Kaohsiung, Taiwan

[4] Univ Oxford, Oxford, England

来源：

2007 2ND IEEE INTERNATIONAL CONFERENCE ON NANO/MICRO ENGINEERED AND MOLECULAR SYSTEMS, VOLS 1-3 | 2007年

关键词：

D O I：

暂无

中图分类号：

TM [电工技术]; TN [电子技术、通信技术];

学科分类号：

0808 ; 0809 ;

摘要：

The development of non-invasive optical fibre sensor array for on-line monitoring of pH in microbioreactors is described. The working principle is based on the optical absorption of phenol red contained in culture medium. Different from other devices of the similar working principle, the proposed device requires less liquid volume (less than 0.8 mu l), is non-invasive, and particularly can be configured as an array. The computer simulation and experimental results revealed that the design of, oval detection chamber can substabtially reduce the response time. Also, the system was proved to be able to detect pH change (pH 6.8-7.8) experienced in normal cell culture.

引用

页码：552 / +

页数：3

共 6 条

[1] Characterization of microtiterplates with integrated optical sensors for oxygen and pH, and their applications to enzyme activity screening, respirometry, and toxicological assays [J].