Dynamics of DNA tumbling in shear to rotational mixed flows: Pathways and periods

被引：37

作者：

Lee, Joo Sung ^{[1
]}

Shaqfeh, Eric S. G.

Muller, Susan J.

机构：

[1] Univ Calif Berkeley, Dept Chem Engn, Berkeley, CA 94720 USA

[2] Stanford Univ, Dept Chem & Mech Engn, Berkeley, CA 94305 USA

来源：

PHYSICAL REVIEW E | 2007年 / 75卷 / 04期

关键词：

D O I：

10.1103/PhysRevE.75.040802

中图分类号：

O35 [流体力学]; O53 [等离子体物理学];

学科分类号：

070204 ; 080103 ; 080704 ;

摘要：

The tumbling dynamics of DNA have been examined via experiments and Brownian dynamics (BD) simulations in mixed flows that vary from pure shear to pure rotation. In shear, tumbling pathways and periods agree well with earlier studies; in rotation-dominated flows, a new tumbling pathway is identified and experimentally observed. Based on these results, we have developed robust scaling laws for DNA tumbling in both shear and rotational flows and have found a critical flow-type parameter for transition from the shearlike flow regime to the rotation-dominated one.

引用

页数：4

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