Granulomatous reaction to hyaluronic acid filler material in oral and perioral region: A case report and review of literature

被引：21

作者：

Alcantara, Carlos Eduardo P. ^{[1
]}

Noronha, Mariana S. ^{[2
]}

Cunha, Joanna F. ^{[2
]}

Flores, Isadora L. ^{[1
]}

Mesquita, Ricardo A. ^{[2
]}

机构：

[1] Univ Fed Juiz De Fora, Dept Odontol, Governador Valadares, MG, Brazil

[2] Univ Fed Minas Gerais, Fac Odontol, Dept Clin Patol & Cirurg Odontol, Belo Horizonte, MG, Brazil

来源：

JOURNAL OF COSMETIC DERMATOLOGY | 2018年 / 17卷 / 04期

关键词：

adverse reactions; dermal fillers; diagnosis; granulomatous reaction; hyaluronic acid; oral granuloma; FOREIGN-BODY REACTION; SOFT-TISSUE FILLERS; DERMAL FILLERS; COSMETIC FILLERS; ADVERSE-REACTIONS; LIP AUGMENTATION; GEL; INJECTION; HYLAFORM((R)); RESTYLANE;

D O I：

10.1111/jocd.12374

中图分类号：

R75 [皮肤病学与性病学];

学科分类号：

100206 ;

摘要：

The use of cosmetic fillers agents in orofacial region has become more often used for esthetic concern. Although adverse effects are rare, some patients may develop foreign body reaction to such fillers. Hyaluronic acid (HA) is a biomaterial in the spotlight, because it is normally present in several tissues of human body. The aim of this study was to report a case of a 54-year-old white woman with granulomatous reaction to the HA located in the lips. In addition, a review of the English-language literature of all previously described cases of this condition in oral and perioral region was performed. The location, clinical features, symptoms, time between injection and reaction, type of treatment and treatment outcome of 17 cases were summarized. The clinical and histopathological examination along with a detailed history about this condition is very important to management of patients with nodular lesions in maxillofacial region.

引用

页码：578 / 583

页数：6

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