Diffusion-weighted magnetic resonance imaging of gallbladder adenocarcinoma: analysis with emphasis on histologic grade

被引：25

作者：

Lee, Nam Kyung ^{[1
]}

Kim, Suk ^{[1
]}

Moon, Jin Il ^{[1
]}

Shin, Nari ^{[2
]}

Kim, Dong Uk ^{[3
]}

Seo, Hyung Il ^{[4
]}

Kim, Hyun Sung ^{[4
]}

Han, Ga Jin ^{[1
]}

Kim, Jin You ^{[1
]}

Lee, Ji Won ^{[1
]}

机构：

[1] Pusan Natl Univ, Sch Med, Pusan Natl Univ Hosp, Dept Radiol,Biomed Res Inst, 305 GuDeok Ro, Busan 602739, South Korea

[2] Pusan Natl Univ, Sch Med, Pusan Natl Univ Hosp, Dept Pathol,Biomed Res Inst, 305 GuDeok Ro, Busan 602739, South Korea

[3] Pusan Natl Univ, Sch Med, Pusan Natl Univ Hosp, Dept Internal Med,Biomed Res Inst, 305 GuDeok Ro, Busan 602739, South Korea

[4] Pusan Natl Univ, Sch Med, Pusan Natl Univ Hosp, Dept Surg,Biomed Res Inst, 305 GuDeok Ro, Busan 602739, South Korea

来源：

CLINICAL IMAGING | 2016年 / 40卷 / 03期

关键词：

Gallbladder; Carcinoma; MRI; DWI; POLYPOID LESIONS; CARCINOMA; MRI; DIFFERENTIATION; CANCER; BENIGN; COEFFICIENT; TOMOGRAPHY; DIAGNOSIS; DISEASE;

D O I：

10.1016/j.clinimag.2016.01.008

中图分类号：

R8 [特种医学]; R445 [影像诊断学];

学科分类号：

1002 ; 100207 ; 1009 ;

摘要：

Purpose: To investigate the value of diffusion-weighted imaging (DWI) for differentiating gallbladder adenocarcinoma from adenoma, and predicting histologic grades of gallbladder adenocarcinoma. Materials and methods: Fourty-three gallbladder adenocarcinomas and 8 adenomas were included. We compared apparent diffusion coefficient (ADC) values between adenocarcinoma and adenoma, and ADC values of gallbladder adenocarcinoma among the histologic grade. Results: Gallbladder adenocarcinoma (1.041 x 10(-3) mm(2)/s) showed significantly lower ADC values than adenoma (2.039 x 10(-3) mm(2)/s) (P<.001). Well-differentiated adenocarcinoma (1.290 x 10(-3) mm(2)/s) showed significantly higher ADC values than higher-grades (1.104 x 10(-3) and 0.915 x 10(-3) mm(2)/s in moderately- and poorly-differentiated, respectively) (P<.001). Conclusion: DWI can help to differentiate gallbladder adenocarcinoma from adenoma, and well-differentiated from higher-grade adenocarcinoma. (C) 2016 Elsevier Inc. All rights reserved.

引用

页码：345 / 351

页数：7

共 34 条

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