Advances in Percutaneous Therapies for Peripheral Artery Disease: Drug-Coated Balloons

被引:5
作者
Al-Bawardy, Rasha F. [1 ]
Waldo, Stephen W. [2 ]
Rosenfield, Kenneth [1 ]
机构
[1] Massachusetts Gen Hosp, Dept Med, Div Cardiol, Boston, MA 02114 USA
[2] VA Eastern Colorado Healthcare Syst, Div Cardiol, Dept Med, Denver, CO USA
关键词
Drug-coated balloons; Peripheral artery disease; In-stent restenosis; Superficial femoral artery; Popliteal artery; Infrapopliteal disease; IN-STENT RESTENOSIS; TRANSLUMINAL ANGIOPLASTY; INFRAPOPLITEAL ARTERIES; POPLITEAL ARTERIES; ELUTING BALLOONS; STANDARD BALLOON; LOWER-EXTREMITY; NITINOL STENTS; TASK-FORCE; PACLITAXEL;
D O I
10.1007/s11886-017-0913-3
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Purpose of Review This review paper provides a summary on the use of drug-coated balloons in peripheral artery disease. It covers the main drug-coated balloon (DCB) trials. It is divided into categories of lesions: superficial femoral artery and popliteal lesions, infra-popliteal lesions and in-stent restenosis. It also includes an overview of the future of DCBs, highlighting the main ongoing trials. Recent Findings The latest research on DCB focuses on newer types of DCBs, mainly paclitaxel-coated but with lower doses. Another area of latest DCB research is its use in superficial femoral artery and popliteal artery in-stent restenosis, with superior outcomes. Summary Drug-coated balloons produce better outcomes than percutaneous transluminal angioplasty alone in de novo and in-stent restenosis lesions of superficial femoral artery and popliteal arteries. More data are needed to demonstrate efficacy and safety of DCBs in infrapopliteal disease. Newer DCBs and adjunctive therapy may provide improved outcomes for peripheral artery disease interventions.
引用
收藏
页数:9
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