Neuronal migration disorders in man

被引：21
作者：
Lammens, M
机构：
[1] Univ Nijmegen, Med Ctr, Dept Pathol 437, NL-6500 HB Nijmegen, Netherlands
[2] Univ Nijmegen, Med Ctr, Dept Neurol, NL-6500 HB Nijmegen, Netherlands
来源：
EUROPEAN JOURNAL OF MORPHOLOGY | 2000年 / 38卷 / 05期
关键词：
lissencephaly; polymicrogyria; subcortical laminar heterotopia; cortical development; neuronal migration defects; meningeal ectopia;
D O I：
10.1076/ejom.38.5.327.7358
中图分类号：
R602 [外科病理学、解剖学]; R32 [人体形态学];
学科分类号：
100101 ;
摘要：
A classification of neuronal migration disorders based on the gross morphology of the disorder with subclassifications according to the cause of the underlying disorder as far as that is known is presented. Emphasis is on disorders of the neocortex. The classical entities classical lissencephaly, cobblestone lissencephaly, polymicrogyria, neuronal heteropia within the white matter and leptomeningeal glial and glioneuronal heterotopia are described. Recent findings on the genetics of neuronal migration disorders are discussed. More subtle structural abnormalities such as cortical dysgenesis or dysplasia remain still more controversial as separate entities.
引用
收藏
页码：327 / 333
页数：7
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