Chemokines and the extracellular matrix: Set of targets for tumor development and treatment

被引：23

作者：

da Silva, Paulo Henrique Rosa ^{[1
]}

Borges, Bruna Cristina ^{[1
]}

Uehara, Isadora Akemi ^{[1
]}

Soldi, Luiz Ricardo ^{[1
]}

de Araujo, Rogerio Agenor ^{[1
]}

Silva, Marcelo Jose Barbosa ^{[1
]}

机构：

[1] Univ Fed Uberlandia, Inst Biomed Sci, Lab Tumor Biomarkers & Osteoimmunol, Uberlandia, MG, Brazil

来源：

CYTOKINE | 2021年 / 144卷

关键词：

Chemokines; Tumor; Extracellular matrix; Recruitment; Adherence; Progress; HEPARAN-SULFATE PROTEOGLYCANS; CELL LUNG-CANCER; CC-CHEMOKINE; GLYCOSAMINOGLYCAN-BINDING; T-CELLS; INFLAMMATORY CHEMOKINES; MONOCLONAL-ANTIBODY; ANTITUMOR IMMUNITY; LIGAND; IN-VIVO;

D O I：

10.1016/j.cyto.2021.155548

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The extracellular matrix (ECM) consists of various molecules that support tissue cells, including proteins, fibronectin, laminin, collagen IV, and glycosaminoglycans. In addition to interactions between the ECM and cells, the ECM also interacts with chemokines, and growth factors, and these interactions ensure cell survival, development, differentiation, and migration of both immune system cells and tumor cells. This review provides an overview of the mechanisms of interaction between the ECM and chemokines, focusing on the tumor microenvironment and the modulation of these elements as a target for therapies in several types of cancer.

引用

页数：9

共 105 条

[81] The CXCL5/CXCR2 axis is sufficient to promote breast cancer colonization during bone metastasis [J].

Romero-Moreno, Ricardo ;

Curtis, Kimberly J. ;

Coughlin, Thomas R. ;

Miranda-Vergara, Maria Cristina ;

Dutta, Shourik ;

Natarajan, Aishwarya ;

Facchine, Beth A. ;

Jackson, Kristen M. ;

Nystrom, Lukas ;

Li, Jun ;

Kaliney, William ;

Niebur, Glen L. ;

Littlepage, Laurie E. .

NATURE COMMUNICATIONS, 2019, 10 (1)

[82] NEUTROPHIL ATTRACTANT ACTIVATION PROTEIN-1 (INTERLEUKIN-8) INDUCES INVITRO NEUTROPHIL MIGRATION BY HAPTOTACTIC MECHANISM [J].

ROT, A .

EUROPEAN JOURNAL OF IMMUNOLOGY, 1993, 23 (01) :303-306

[83] The CXCL8/IL-8 chemokine family and its receptors in inflammatory diseases [J].

Russo, Remo C. ;

Garcia, Cristiana C. ;

Teixeira, Mauro M. ;

Amaral, Flavio A. .

EXPERT REVIEW OF CLINICAL IMMUNOLOGY, 2014, 10 (05) :593-619

[84] Heparan sulfate proteoglycans in invasion and metastasis [J].

Sanderson, RD .

SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY, 2001, 12 (02) :89-98

[85] A first-in-human, first-in-class, phase I study of carlumab (CNTO 888), a human monoclonal antibody against CC-chemokine ligand 2 in patients with solid tumors [J].

Sandhu, Shahneen K. ;

Papadopoulos, Kyri ;

Fong, Peter C. ;

Patnaik, Amita ;

Messiou, Christina ;

Olmos, David ;

Wang, George ;

Tromp, Brenda J. ;

Puchalski, Thomas A. ;

Balkwill, Frances ;

Berns, Birge ;

Seetharam, Shobha ;

de Bono, Johann S. ;

Tolcher, Anthony W. .

CANCER CHEMOTHERAPY AND PHARMACOLOGY, 2013, 71 (04) :1041-1050

[86] Roles of heparan-sulphate glycosaminoglycans in cancer [J].

Sasisekharan, R ;

Shriver, Z ;

Venkataraman, G ;

Narayanasami, U .

NATURE REVIEWS CANCER, 2002, 2 (07) :521-528

[87]

Shriver Zachary, 2012, Handb Exp Pharmacol, P159, DOI 10.1007/978-3-642-23056-1_8

[88] Expression of the chemokine CXCL14 in the tumour stroma is an independent marker of survival in breast cancer [J].

Sjoberg, Elin ;

Augsten, Martin ;

Bergh, Jonas ;

Jirstrom, Karin ;

Ostman, Arne .

BRITISH JOURNAL OF CANCER, 2016, 114 (10) :1117-1124

[89] CXCL12/CXCR4/CXCR7 chemokine axis and cancer progression [J].

Sun, Xueqing ;

Cheng, Guangcun ;

Hao, Mingang ;

Zheng, Jianghua ;

Zhou, Xiaoming ;

Zhang, Jian ;

Taichman, Russell S. ;

Pienta, Kenneth J. ;

Wang, Jianhua .

CANCER AND METASTASIS REVIEWS, 2010, 29 (04) :709-722

[90] Snail promotes ovarian cancer progression by recruiting myeloid-derived suppressor cells via CXCR2 ligand upregulation [J].

Taki, Mana ;

Abiko, Kaoru ;

Baba, Tsukasa ;

Hamanishi, Junzo ;

Yamaguchi, Ken ;

Murakami, Ryusuke ;

Yamanoi, Koji ;

Horikawa, Naoki ;

Hosoe, Yuko ;

Nakamura, Eijiro ;

Sugiyama, Aiko ;

Mandai, Masaki ;

Konishi, Ikuo ;

Matsumura, Noriomi .

NATURE COMMUNICATIONS, 2018, 9

← 2 3 4 5 6 7 8 9 10 11 →