Chemokines and the extracellular matrix: Set of targets for tumor development and treatment

被引：23

作者：

da Silva, Paulo Henrique Rosa ^{[1
]}

Borges, Bruna Cristina ^{[1
]}

Uehara, Isadora Akemi ^{[1
]}

Soldi, Luiz Ricardo ^{[1
]}

de Araujo, Rogerio Agenor ^{[1
]}

Silva, Marcelo Jose Barbosa ^{[1
]}

机构：

[1] Univ Fed Uberlandia, Inst Biomed Sci, Lab Tumor Biomarkers & Osteoimmunol, Uberlandia, MG, Brazil

来源：

CYTOKINE | 2021年 / 144卷

关键词：

Chemokines; Tumor; Extracellular matrix; Recruitment; Adherence; Progress; HEPARAN-SULFATE PROTEOGLYCANS; CELL LUNG-CANCER; CC-CHEMOKINE; GLYCOSAMINOGLYCAN-BINDING; T-CELLS; INFLAMMATORY CHEMOKINES; MONOCLONAL-ANTIBODY; ANTITUMOR IMMUNITY; LIGAND; IN-VIVO;

D O I：

10.1016/j.cyto.2021.155548

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The extracellular matrix (ECM) consists of various molecules that support tissue cells, including proteins, fibronectin, laminin, collagen IV, and glycosaminoglycans. In addition to interactions between the ECM and cells, the ECM also interacts with chemokines, and growth factors, and these interactions ensure cell survival, development, differentiation, and migration of both immune system cells and tumor cells. This review provides an overview of the mechanisms of interaction between the ECM and chemokines, focusing on the tumor microenvironment and the modulation of these elements as a target for therapies in several types of cancer.

引用

页数：9

共 105 条

[41] Extracellular matrix regulation of drug resistance in small-cell lung cancer [J].

Hodkinson, P. S. ;

Mackinnon, A. C. ;

Sethi, T. .

INTERNATIONAL JOURNAL OF RADIATION BIOLOGY, 2007, 83 (11-12) :733-741

[42] Interaction of chemokines and glycosaminoglycans: A new twist in the regulation of chemokine function with opportunities for therapeutic intervention [J].

Johnson, Z ;

Proudfoot, AE ;

Handel, TM .

CYTOKINE & GROWTH FACTOR REVIEWS, 2005, 16 (06) :625-636

[43] Mesenchymal stem cells within tumour stroma promote breast cancer metastasis [J].

Karnoub, Antoine E. ;

Dash, Ajeeta B. ;

Vo, Annie P. ;

Sullivan, Andrew ;

Brooks, Mary W. ;

Bell, George W. ;

Richardson, Andrea L. ;

Polyak, Kornelia ;

Tubo, Ross ;

Weinberg, Robert A. .

NATURE, 2007, 449 (7162) :557-U4

[44] Ulocuplumab (BMS-936564 / MDX1338): a fully human anti-CXCR4 antibody induces cell death in chronic lymphocytic leukemia mediated through a reactive oxygen species-dependent pathway [J].

Kashyap, Manoj K. ;

Kumar, Deepak ;

Jones, Harrison ;

Amaya-Chanaga, Carlos I. ;

Choi, Michael Y. ;

Melo-Cardenas, Johanna ;

Ale-Ali, Amine ;

Kuhne, Michelle R. ;

Sabbatini, Peter ;

Cohen, Lewis J. ;

Shelat, Suresh G. ;

Rassenti, Laura Z. ;

Kipps, Thomas J. ;

Cardarelli, Pina M. ;

Castro, Januario E. .

ONCOTARGET, 2016, 7 (03) :2809-2822

[45] IL-22+CD4+ T Cells Promote Colorectal Cancer Stemness via STAT3 Transcription Factor Activation and Induction of the Methyltransferase DOT1L [J].

Kryczek, Ilona ;

Lin, Yanwei ;

Nagarsheth, Nisha ;

Peng, Dongjun ;

Zhao, Lili ;

Zhao, Ende ;

Vatan, Linda ;

Szeliga, Wojciech ;

Dou, Yali ;

Owens, Scott ;

Zgodzinski, Witold ;

Majewski, Marek ;

Wallner, Grzegorz ;

Fang, Jingyuan ;

Huang, Emina ;

Zou, Weiping .

IMMUNITY, 2014, 40 (05) :772-784

[46] Lymphocyte CC chemokine receptor 9 and epithelial thymus-expressed chemokine (TECK) expression distinguish the small intestinal immune compartment: Epithelial expression of tissue-specific chemokines as an organizing principle in regional immunity [J].

Kunkel, EJ ;

Campbell, JJ ;

Haraldsen, G ;

Pan, JL ;

Boisvert, J ;

Roberts, AI ;

Ebert, EC ;

Vierra, MA ;

Goodman, SB ;

Genovese, MC ;

Wardlaw, AJ ;

Greenberg, HB ;

Parker, CM ;

Butcher, EC ;

Andrew, DP ;

Agace, WW .

JOURNAL OF EXPERIMENTAL MEDICINE, 2000, 192 (05) :761-767

[47] Relationships between glycosaminoglycan and receptor binding sites in chemokines - the CXCL12 example [J].

Laguri, Cedric ;

Arenzana-Seisdedos, Fernando ;

Lortat-Jacob, Hugues .

CARBOHYDRATE RESEARCH, 2008, 343 (12) :2018-2023

[48] Recruitment of γδ T lymphocytes to tumors A new role for the pleiotropic chemokine CCL2 [J].

Lanca, Telma ;

Silva-Santos, Bruno .

ONCOIMMUNOLOGY, 2013, 2 (08)

[49] Protective Role of the Inflammatory CCR2/CCL2 Chemokine Pathway through Recruitment of Type 1 Cytotoxic γδ T Lymphocytes to Tumor Beds [J].

Lanca, Telma ;

Costa, Maria Fernanda ;

Goncalves-Sousa, Natacha ;

Rei, Margarida ;

Grosso, Ana Rita ;

Penido, Carmen ;

Silva-Santos, Bruno .

JOURNAL OF IMMUNOLOGY, 2013, 190 (12) :6673-6680

[50] Identification of the glycosaminoglycan binding site of the CC chemokine, MCP-1 -: Implications for structure and function in vivo [J].

Lau, EK ;

Paavola, CD ;

Johnson, Z ;

Gaudry, JP ;

Geretti, E ;

Borlat, F ;

Kungl, AJ ;

Proudfoot, AE ;

Handel, TM .

JOURNAL OF BIOLOGICAL CHEMISTRY, 2004, 279 (21) :22294-22305

← 1 2 3 4 5 6 7 8 9 10 →