Direct Synthesis of 1,4-Disubstituted-5-alumino-1,2,3-triazoles: Copper-Catalyzed Cycloaddition of Organic Azides and Mixed Aluminum Acetylides

被引：124

作者：

Zhou, Yuhan ^{[1
,2
]}

Lecourt, Thomas ^{[1
]}

Micouin, Laurent ^{[1
]}

机构：

[1] Univ Paris 05, UMR 8638, CNRS, Fac Pharm, F-75006 Paris, France

[2] Dalian Univ Technol, State Key Lab Fine Chem, Sch Chem Engn, Dalian 116012, Peoples R China

来源：

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION | 2010年 / 49卷 / 14期

关键词：

aluminum; click chemistry; copper; cycloaddition; regioselectivity; TERMINAL ALKYNES; DEPROTONATIVE METALATION; BORONIC ACIDS; REAGENTS; HETEROCYCLES; ARYL; EXCHANGE; ARENES; BASE;

D O I：

10.1002/anie.200907016

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

"Chemical Equation Presented" Al together now: Aluminotriazoles are obtained in a fully chemo- and regioselective manner by a copper-catalyzed cycloaddition of organic azides with mixed-aluminum acetylides (see scheme). The carbon-aluminum bond, which is unaffected by the first transformation, is still able to react further with different electrophiles. © 2010 Wiley-VCH Verlag GmbH & Co. KGaA.

引用

页码：2607 / 2610

页数：4

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