Atypical chronic myeloid leukaemia with trisomy 21 mosaicism as a sole chromosomal abnormality

被引：2

作者：

Benedek, D ^{[1
]}

Kiehl, M ^{[1
]}

Draube, A ^{[1
]}

Chemnitz, J ^{[1
]}

Diehl, V ^{[1
]}

Sohngen, D ^{[1
]}

机构：

[1] Univ Hosp Koln, Dept Internal Med 1, D-50924 Cologne, Germany

来源：

LEUKEMIA & LYMPHOMA | 2000年 / 38卷 / 5-6期

关键词：

CML; Chronic myeloid leukemia; trisomy; 21; mosaicism; CMML; myelodysplasia; chronic myelomonocytic leukemia;

D O I：

10.3109/10428190009059285

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

We present a 46-year-old patient with Ph-chromosome negative, bcr-negative chronic myeloid leukaemia (CML) in accelerated phase with a clonal trisomy 21 in the leukaemic blast cells. A rapid progress of disease with appearance of monocytosis is described, showing similar features to chronic myelomonocytic leukaemia (CMML), Heterogeneous characteristics and possible distinction of these two entities are discussed.

引用

页码：639 / +

页数：7

共 16 条

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