Vaccine-induced hepatitis C virus-specific CD8+ T cells do not always help

被引：4
作者：
Wieland, Dominik [1 ,2 ,3 ]
Thimme, Robert [1 ]
机构：
[1] Univ Hosp Freiburg, Dept Med 2, Hugstetter Str 55, D-79106 Freiburg, Germany
[2] Univ Freiburg, Spemann Grad Sch Biol & Med, Hugstetter Str 55, D-79106 Freiburg, Germany
[3] Univ Freiburg, Fac Biol, Hugstetter Str 55, D-79106 Freiburg, Germany
来源：
HEPATOLOGY | 2016年 / 63卷 / 05期
关键词：
HCV; IMMUNITY;
D O I：
10.1002/hep.28388
中图分类号：
R57 [消化系及腹部疾病];
学科分类号：
摘要：
引用
收藏
页码：1411 / 1414
页数：4
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  • [1] Coexpression of PD-1, 2B4, CD160 and KLRG1 on Exhausted HCV-Specific CD8+T Cells Is Linked to Antigen Recognition and T Cell Differentiation
    Bengsch, Bertram
    Seigel, Bianca
    Ruhl, Marianne
    Timm, Joerg
    Kuntz, Martin
    Blum, Hubert E.
    Pircher, Hanspeter
    Thimme, Robert
    [J]. PLOS PATHOGENS, 2010, 6 (06)
  • [2] Persistent hepatitis C viral replication despite priming of functional CD8+ T cells by combined therapy with a vaccine and a direct-acting antiviral
    Callendret, Benoit
    Eccleston, Heather B.
    Satterfield, William
    Capone, Stefania
    Folgori, Antonella
    Cortese, Riccardo
    Nicosia, Alfredo
    Walker, Christopher M.
    [J]. HEPATOLOGY, 2016, 63 (05) : 1442 - 1454
  • [3] T-Cell Immunity and Hepatitis C Virus Reinfection After Cure of Chronic Hepatitis C With an Interferon-Free Antiviral Regimen in a Chimpanzee
    Callendret, Benoit
    Eccleston, Heather B.
    Hall, Shelby
    Satterfield, William
    Capone, Stefania
    Folgori, Antonella
    Cortese, Riccardo
    Nicosia, Alfredo
    Walker, Christopher M.
    [J]. HEPATOLOGY, 2014, 60 (05) : 1531 - 1540
  • [4] HCV persistence and immune evasion in the absence of memory T cell help
    Grakoui, A
    Shoukry, NH
    Woollard, DJ
    Han, JH
    Hanson, HL
    Ghrayeb, J
    Murthy, KK
    Rice, CM
    Walker, CM
    [J]. SCIENCE, 2003, 302 (5645) : 659 - 662
  • [5] Innate and adaptive immune responses in HCV infections
    Heim, Markus H.
    Thimme, Robert
    [J]. JOURNAL OF HEPATOLOGY, 2014, 61 : S14 - S25
  • [6] Hepatitis C Virus (HCV) Sequence Variation Induces an HCV-Specific T-Cell Phenotype Analogous to Spontaneous Resolution
    Kasprowicz, Victoria
    Kang, Yu-Hoi
    Lucas, Michaela
    zur Wiesch, Julian Schulze
    Kuntzen, Thomas
    Fleming, Vicki
    Nolan, Brian E.
    Longworth, Steven
    Berical, Andrew
    Bengsch, Bertram
    Thimme, Robert
    Lewis-Ximenez, Lia
    Allen, Todd M.
    Kim, Arthur Y.
    Klenerman, Paul
    Lauer, Georg M.
    [J]. JOURNAL OF VIROLOGY, 2010, 84 (03) : 1656 - 1663
  • [7] Chronic hepatitis C viral infection subverts vaccine-induced T-cell immunity in humans
    Kelly, Christabel
    Swadling, Leo
    Capone, Stefania
    Brown, Anthony
    Richardson, Rachel
    Halliday, John
    von Delft, Annette
    Oo, Ye
    Mutimer, David
    Kurioka, Ayako
    Hartnell, Felicity
    Collier, Jane
    Ammendola, Virginia
    Del Sorbo, Mariarosaria
    Grazioli, Fabiana
    Esposito, Maria Luisa
    Di Marco, Stefania
    Siani, Loredana
    Traboni, Cinzia
    Hill, Adrian V. S.
    Colloca, Stefano
    Nicosia, Alfredo
    Cortese, Riccardo
    Folgori, Antonella
    Klenerman, Paul
    Barnes, Eleanor
    [J]. HEPATOLOGY, 2016, 63 (05) : 1455 - 1470
  • [8] Hepatic Immune Regulation and Its Involvement in Viral Hepatitis Infection
    Knolle, Percy A.
    Thimme, Robert
    [J]. GASTROENTEROLOGY, 2014, 146 (05) : 1193 - 1207
  • [9] Restoration of HCV-specific CD8+T cell function by interferon-free therapy
    Martin, Bianca
    Hennecke, Nadine
    Lohmann, Volker
    Kayser, Antonin
    Neumann-Haefelin, Christoph
    Kukolj, George
    Boecher, Wulf-Otto
    Thimme, Robert
    [J]. JOURNAL OF HEPATOLOGY, 2014, 61 (03) : 538 - 543
  • [10] Immune Responses to HCV and Other Hepatitis Viruses
    Park, Su-Hyung
    Rehermann, Barbara
    [J]. IMMUNITY, 2014, 40 (01) : 13 - 24
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