miR-1-2 gets to the heart of the matter

被引：39

作者：

Mishima, Yuichiro ^{[1
]}

Stahlhut, Carlos ^{[1
]}

Giraldez, Antonio J. ^{[1
]}

机构：

[1] Yale Univ, Sch Med, Dept Genet, New Haven, CT 06510 USA

来源：

CELL | 2007年 / 129卷 / 02期

关键词：

D O I：

10.1016/j.cell.2007.04.008

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Although many microRNAs (miRNAs) and their targets have been identified, the importance of miRNAs; in vivo is still unclear In this issue, Zhao et al. (2007) generate mice deficient in a cardiac-specif ic miRNA, miR-1 -2, and reveal that this microRNA plays a crucial role in heart development and physiology.

引用

页码：247 / 249

页数：3

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