Environmentally friendly C-glycosylation of phloroacetophenone with unprotected D-glucose using scandium(III) trifluoromethanesulfonate in aqueous media:: key compounds for the syntheses of mono- and di-C-glucosylflavonoids

被引：46

作者：

Sato, S ^{[1
]}

Akiya, T ^{[1
]}

Suzuki, T ^{[1
]}

Onodera, J ^{[1
]}

机构：

[1] Yamagata Univ, Fac Engn, Dept Chem & Chem Engn, Yamagata 9928510, Japan

来源：

CARBOHYDRATE RESEARCH | 2004年 / 339卷 / 15期

关键词：

C-glycosylflavonoid; direct C-glycosylation; unprotected glucose; Sc(OTf)(3); aqueous media; recycling;

D O I：

10.1016/j.carres.2004.07.023

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The direct C-glycosylation of phloroacetophenone with an unprotected D-glucose in aqueous media using scandium(III) trifluoromethanesulfonate (Sc(OTf)(3)) as the catalyst, gave mono- and bis-C-beta-glycosylic compounds in highest total yield of 81%. The second and third use of the recovered Sc(OTf)(3) afforded them in total yields of 56% and 53%, respectively. (C) 2004 Elsevier Ltd. All rights reserved.

引用

页码：2611 / 2614

页数：4

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