Quinone diterpenes from Salvia species: chemistry, botany, and biological activity

被引:38
作者
Bisio, Angela [1 ]
Pedrelli, Francesca [1 ]
D'Ambola, Massimiliano [2 ]
Labanca, Fabiana [3 ]
Schito, Anna Maria [4 ]
Govaerts, Rafael [5 ]
De Tommasi, Nunziatina [2 ]
Milella, Luigi [3 ]
机构
[1] Univ Genoa, Dipartimento Farm, Genoa, Italy
[2] Univ Salerno, Dipartimento Farm, Via Giovanni Paolo II, Fisciano, SA, Italy
[3] Univ Basilicata, Dipartimento Sci, Viale Ateneo Lucano 10, I-85100 Potenza, Italy
[4] Univ Genoa, Sez Microbiol, Dipartimento Sci Chirurg & Diagnost Integrate, Largo Rosanna Benzi 8, I-16145 Genoa, Italy
[5] Kew, Royal Bot Gardens, Jodrell Lab, Biodivers Informat & Spatial Anal, Kew Rd, Richmond TW9 3DS, Surrey, England
关键词
Salvia; Abietane quinone diterpenes; Taxonomical information; Antimicrobial; Biological activity; TANSHINONE IIA PROTECTS; REARRANGED ABIETANE DITERPENES; EUPHRATICA SENSU-LATO; ICETEXANE DITERPENOIDS; AERIAL PARTS; CYTOTOXIC ACTIVITY; IN-VITRO; ANTIBACTERIAL DITERPENES; BIOACTIVE DITERPENOIDS; PHYLOGENETIC-RELATIONSHIPS;
D O I
10.1007/s11101-019-09633-z
中图分类号
Q94 [植物学];
学科分类号
071001 ;
摘要
A total of 175 abietane quinone diterpenes with ortho- or para-quinone chromophore, namely 11,12-ortho-quinone abietane, 11,14-para-quinone abietane, seco-abietane and abeo-abietanes quinones were surveyed from 130 species of Salvia of central Asia/Mediterranean area, eastern Asia, and Central and South America. An organized information on the phytochemistry and the biological activities, i.e. anti-cancer, antioxidant, anxiolytic and antidepressant, anti-obesity, antinflammatory, as well as antimicrobial and toxicological aspects of these compounds was provided. Due to the many nomenclatural mistakes caused by the abundance of data, and the need to provide the plant knowledge for further chemotaxonomic studies, the results about the botany and the taxonomy of the plant source of these compounds were also summarized.
引用
收藏
页码:665 / 842
页数:178
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