National treatment programme of hepatitis C in Egypt: Hepatitis C virus model of care

被引:139
作者
El-Akel, W. [1 ]
El-Sayed, M. H. [2 ]
El Kassas, M. [3 ]
El-Serafy, M. [1 ]
Khairy, M. [1 ]
Elsaeed, K. [4 ]
Kabil, K. [5 ]
Hassany, M. [6 ]
Shawky, A. [4 ]
Yosry, A. [1 ]
Shaker, M. K. [7 ]
ElShazly, Y. [4 ]
Waked, I. [8 ]
Esmat, G. [1 ]
Doss, W. [1 ]
机构
[1] Cairo Univ, Fac Med, Endem Med & Hepatol, Cairo, Egypt
[2] Ain Shams Univ, Pediat Hematol Oncol, Cairo, Egypt
[3] Helwan Univ, Fac Med, Endem Med, Cairo, Egypt
[4] Ain Shams Univ, Internal Med, Fac Med, Cairo, Egypt
[5] Cairo Univ, New Pediat Children Hosp, Cairo, Egypt
[6] Natl Hepatol & Trop Med Res Inst, Dept Trop Dis, Cairo, Egypt
[7] Ain Shams Univ, Trop Med, Fac Med, Cairo, Egypt
[8] Natl Liver Inst, Dept Hepatol, Shibin Al Kawm, Egypt
关键词
chronic HCV; Egypt; model of care; National Committee for Control of Viral Hepatitis; TRANSMISSION; INFECTION; DISEASE; SPREAD; RISK;
D O I
10.1111/jvh.12668
中图分类号
R57 [消化系及腹部疾病];
学科分类号
摘要
Hepatitis C virus (HCV) infection is a major health problem in Egypt as the nation bears the highest prevalence rate worldwide. This necessitated establishing a novel model of care (MOC) to contain the epidemic, deliver patient care and ensure global treatment access. In this review, we describe the process of development of the Egyptian model and future strategies for sustainability. Although the magnitude of the HCV problem was known for many years, the HCV MOC only came into being in 2006 with the establishment of the National Committee for Control of Viral Hepatitis (NCCVH) to set up and implement a national control strategy for the disease and other causes of viral hepatitis. The strategy outlines best practices for patient care delivery by applying a set of service principles through identified clinical streams and patient flow continuums. The Egyptian national viral hepatitis treatment programme is considered one of the most successful and effective public health programmes. To date, more than one million patients were evaluated and more than 850000 received treatment under the umbrella of the programme since 2006. The NCCVH has been successful in establishing a strong infrastructure for controlling viral hepatitis in Egypt. It established a nationwide network of digitally connected viral hepatitis-specialized treatment centres covering the country map to enhance treatment access. Practice guidelines suiting local circumstances were issued and regularly updated and are applied in all affiliated centres. This review illustrates the model and the successful Egyptian experience. It sets an exemplar for states, organizations and policy-makers setting up programmes for care and management of people with hepatitis C.
引用
收藏
页码:262 / 267
页数:6
相关论文
共 17 条
[1]   Changing pattern of hepatitis C virus spread in rural areas of Egypt [J].
Arafa, N ;
El Hoseiny, M ;
Rekacewicz, C ;
Bakr, I ;
El-Kafrawy, S ;
El Daly, M ;
Aoun, S ;
Marzouk, D ;
Mohamed, MK ;
Fontanet, A .
JOURNAL OF HEPATOLOGY, 2005, 43 (03) :418-424
[2]  
Craxì A, 2011, J HEPATOL, V55, P245, DOI 10.1016/j.jhep.2011.02.023
[3]   The Effect of Peginterferon Alpha-2a vs. Peginterferon Alpha-2b in Treatment of Naive Chronic HCV Genotype-4 Patients: A Single Centre Egyptian Study [J].
El Raziky, Maissa ;
Fathalah, Waleed Fouad ;
El-akel, Wafaa Ahmed ;
Salama, Ahmed ;
Esmat, Gamal ;
Mabrouk, Mahassen ;
Salama, Rabab Mamoun ;
Khatab, Hany Mahmoud .
HEPATITIS MONTHLY, 2013, 13 (05)
[4]  
El Sayed Nasr, 2012, Morbidity and Mortality Weekly Report, V61, P545
[5]  
ELZENATI F, 2008, EGYPT DEMOGRAPHIC HL
[6]   The role of parenteral antischistosomal therapy in the spread of hepatitis C virus in Egypt [J].
Frank, C ;
Mohamed, MK ;
Strickland, GT ;
Lavanchy, D ;
Arthur, RR ;
Magder, LS ;
El Khoby, T ;
Abdel-Wahab, Y ;
Ohn, EA ;
Anwar, W ;
Sallam, I .
LANCET, 2000, 355 (9207) :887-891
[7]   Global burden of disease (GBD) for hepatitis C [J].
Hutin, Y ;
Kitler, ME ;
Dore, GJ ;
Perz, JF ;
Armstrong, GL ;
Dusheiko, G ;
Ishibashi, H ;
Grob, P ;
Kew, M ;
Marcellin, P ;
Seeff, LB ;
Beutels, P ;
Nelson, C ;
Stein, C ;
Zurn, P ;
Clifford, G ;
Vranckx, R ;
Alberti, A ;
Hallaj, ZS ;
Hadler, S ;
Lavanchy, D .
JOURNAL OF CLINICAL PHARMACOLOGY, 2004, 44 (01) :20-29
[8]   HCV iatrogenic and intrafamilial transmission in Greater Cairo, Egypt [J].
Jimenez, A. Paez ;
Eldin, N. Sharaf ;
Rimlinger, F. ;
El-Daly, M. ;
El-Hariri, H. ;
El-Hoseiny, M. ;
Mohsen, A. ;
Mostafa, A. ;
Delarocque-Astagneau, E. ;
Abdel-Hamid, M. ;
Fontanet, A. ;
Mohamed, M. K. ;
Thiers, V. .
GUT, 2010, 59 (11) :1554-1560
[9]   Injection Drug Use Is a Risk Factor for HCV Infection in Urban Egypt [J].
Jimenez, Adela Paez ;
Mohamed, Mostafa K. ;
Eldin, Noha Sharaf ;
Abou Seif, Hasnaa ;
El Aidi, Said ;
Sultan, Yehia ;
Elsaid, Nasr ;
Rekacewicz, Claire ;
El-Hoseiny, Mostafa ;
El-Daly, May ;
Abdel-Hamid, Mohamed ;
Fontanet, Arnaud .
PLOS ONE, 2009, 4 (09)
[10]   The prevalence of hepatitis C virus infection in Egypt 2015: implications for future policy on prevention and treatment [J].
Kandeel, Amr ;
Genedy, Mohamad ;
El-Refai, Samir ;
Funk, Anna L. ;
Fontanet, Arnaud ;
Talaat, Maha .
LIVER INTERNATIONAL, 2017, 37 (01) :45-53