Antibody response to cancer/testis (CT) antigens: A prognostic marker in cancer patients

被引:14
作者
Ohue, Yoshihiro [1 ]
Wada, Hisashi [2 ]
Oka, Mikio [1 ]
Nakayama, Eiichi [3 ]
机构
[1] Kawasaki Med Sch, Dept Resp Med, Kurashiki, Okayama, Japan
[2] Osaka Univ, Grad Sch Med, Dept Clin Res Tumor Immunol, Suita, Osaka, Japan
[3] Kawasaki Univ Med Welf, Fac Hlth & Welf, Kurashiki, Okayama, Japan
关键词
cancer/testis (CT) antigen; NY-ESO-1; XAGE1 (GAGED2a); overall survival; spontaneous antibody response; NY-ESO-1;
D O I
10.4161/21624011.2014.970032
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
Immune responses to tumor antigens have been reported in cancer patients. However, the relevance of such spontaneous immune responses to the clinical course has not been studied extensively. We showed that the overall survival of patients with antibodies against NY-ESO-1 or XAGE1 (GAGED2a) antigen was prolonged in gastric or lung cancer patients, respectively.
引用
收藏
页码:e970032 / 1
页数:3
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