CogEvo, a cognitive function balancer, is a sensitive and easy psychiatric test battery for age-related cognitive decline

被引:19
作者
Ichii, Sadanobu [1 ]
Nakamura, Takumi [1 ,2 ]
Kawarabayashi, Takeshi [1 ,2 ,3 ]
Takatama, Masamitsu [3 ]
Ohgami, Tetsuya [4 ]
Ihara, Kazushige [1 ]
Shoji, Mikio [1 ,3 ,5 ]
机构
[1] Hirosaki Univ, Grad Sch Med, Dept Social Med, Hirosaki, Aomori, Japan
[2] Gunma Univ Hosp, Dept Neurol, Maebashi, Gumma, Japan
[3] Geriatr Res Inst & Hosp, Dementia Res Ctr, Dept Neurol, 3-26-8 Ootomo Machi, Maebashi, Gumma 3710847, Japan
[4] Aomori Univ, Dept Pharmacol, Aomori, Japan
[5] Gunma Univ, Grad Sch Med, Dept Neurobiol & Behav, Maebashi, Gumma, Japan
关键词
age-related cognitive decline; cognitive function balancer; computer-aided psychiatric test battery; MINI-MENTAL-STATE; ALZHEIMERS-DISEASE; NATIONAL INSTITUTE; RESEARCH FRAMEWORK; DEMENTIA; CANTAB;
D O I
10.1111/ggi.13847
中图分类号
R592 [老年病学]; C [社会科学总论];
学科分类号
03 ; 0303 ; 100203 ;
摘要
Aim We examined whether a newly developed computer-aided neuropsychiatric series of test, CogEvo, is necessary and sufficient for the evaluation of cognitive function in older people. Methods A total of 272 participants in worthwhile life activity for the prevention of decline in mobility and cognitive function were administered tests every week at 33 locations in Fukaura-machi, Japan. Basic profile information, a Mini-Mental State Examination (MMSE), a CogEvo and a clock drawing test were used in the present study. Results Our results are summarized as: (i) the total score of the CogEvo and MMSE tests decreased significantly according to age and in age group analysis; (ii) scores from the CogEvo and MMSE tests showed a significant correlation; (iii) MMSE scores showed marked ceiling effects; (iv) analysis of cognitive domains, such as orientation, attention, memory and executive function, and spatial cognition using CogEvo showed significant age-dependent impairment; (v) CogEvo discriminated three score groups of MMSE results with sensitivity and specificity of 70% and 60% in the <23 score group, 78% and 54% in the 24-26 score group, and 85% and 70% in the >27 score group, respectively; (vi) CogEvo memory tests reflected more detailed recall function than registration function; and (vii) CogEvo spatial cognition test results were correlated with test items of the MMSE and clock drawing tests. Conclusions CogEvo is an easy and potentially useful computer-aided test battery that can be used to evaluate age-related or pathological decline in cognitive function from middle age and in preclinical stages of dementia. Geriatr Gerontol Int 2019; center dot center dot: center dot center dot-center dot center dot.
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收藏
页码:248 / 255
页数:8
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