Generation of site-specific DARPin® drug conjugates using EGFR as a model system

被引：0

作者：

Laviolette, Laura A. ^{[1
]}

Guidi, Cynthia J. ^{[1
]}

Reichen, Christian ^{[2
]}

Qiu, Qifeng ^{[1
]}

Harris, Luke ^{[1
]}

Schildknecht, Patricia ^{[2
]}

Fischer, Stefanie ^{[2
]}

Arany, Zita ^{[2
]}

Hospodarsch, Tanja ^{[2
]}

Skaletskaya, Anna ^{[1
]}

Fuller, Megan ^{[1
]}

Abbott, Stephen ^{[1
]}

McCarthy, Rebecca ^{[1
]}

Lee, Jenny ^{[1
]}

Francisco, Katherine ^{[1
]}

Sinkevicius, Kerstin ^{[1
]}

Adams, Sharlene ^{[1
]}

Espelin, Christopher ^{[1
]}

Reid, Emily ^{[1
]}

Li, Wei ^{[1
]}

Marashio, Carla ^{[1
]}

Donahue, Kerry ^{[1
]}

Hicks, Stuart ^{[1
]}

Snell, Dan ^{[2
]}

机构：

[1] ImmunoGen Inc, Waltham, MA USA

[2] Mol Partners AG, Zurich, Switzerland

来源：

CANCER RESEARCH | 2019年 / 79卷 / 13期

关键词：

D O I：

10.1158/1538-7445.AM2019-215

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

215

引用

页数：2

共 50 条

[1] Next-generation site-specific antibody-drug conjugates using the SMARTagTM technology platform
Kudirka, Romas
CANCER RESEARCH, 2015, 75
[2] Site-specific antibody drug conjugates for cancer therapy
Panowski, Siler
Bhakta, Sunil
Raab, Helga
Polakis, Paul
Junutula, Jagath R.
MABS, 2014, 6 (01) : 34 - 45
[3] Current Status: Site-Specific Antibody Drug Conjugates
Dominik Schumacher
Christian P. R. Hackenberger
Heinrich Leonhardt
Jonas Helma
Journal of Clinical Immunology, 2016, 36 : 100 - 107
[4] A general approach to site-specific antibody drug conjugates
Tian, Feng
Lu, Yingchun
Manibusan, Anthony
Sellers, Aaron
Tran, Hon
Sun, Ying
Phuong, Trung
Barnett, Richard
Hehli, Brad
Song, Frank
DeGuzman, Michael J.
Ensari, Semsi
Pinkstaff, Jason K.
Sullivan, Lorraine M.
Biroc, Sandra L.
Cho, Ho
Schultz, Peter G.
DiJoseph, John
Dougher, Maureen
Ma, Dangshe
Dushin, Russell
Leal, Mauricio
Tchistiakova, Lioudmila
Feyfant, Eric
Gerber, Hans-Peter
Sapra, Puja
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2014, 111 (05) : 1766 - 1771
[5] Current Status: Site-Specific Antibody Drug Conjugates
Schumacher, Dominik
Hackenberger, Christian P. R.
Leonhardt, Heinrich
Helma, Jonas
JOURNAL OF CLINICAL IMMUNOLOGY, 2016, 36 : S100 - S107
[6] Efficient Preparation of Site-Specific Antibody Drug Conjugates Using Phosphopantetheinyl Transferases
Gruenewald, Jan
Klock, Heath E.
Cellitti, Susan E.
Bursulaya, Badry
McMullan, Daniel
Jones, David H.
Chiu, Hsien-Po
Wang, Xing
Patterson, Paula
Zhou, Huanfang
Vance, Julie
Nigoghossian, Edward
Tong, Hung
Daniel, Dylan
Mallet, William
Ou, Weijia
Uno, Tetsuo
Brock, Ansgar
Lesley, Scott A.
Geierstanger, Bernhard H.
BIOCONJUGATE CHEMISTRY, 2015, 26 (12) : 2554 - 2562
[7] Site-Specific Antibody Drug Conjugates Using Streamlined Expressed Protein Ligation
Frutos, Silvia
Luis Hernandez, Jose
Otero, Anabel
Calvis, Carme
Adan, Jaume
Mitjans, Francesc
Vila-Perello, Miguel
BIOCONJUGATE CHEMISTRY, 2018, 29 (11) : 3503 - 3508
[8] Polymeric conjugates of drugs and antibodies for site-specific drug delivery
Ulbrich, K
Strohalm, J
Subr, V
Plocova, D
Duncan, R
Rihova, B
MACROMOLECULAR SYMPOSIA, 1996, 103 : 177 - 192
[9] Cysteine arylation to produce site-specific antibody drug conjugates
Pentelute, Bradley
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2018, 256
[10] Efficient Preparation of Site-Specific Antibody-Drug Conjugates Using Cysteine Insertion
Dimasi, Nazzareno
Fleming, Ryan
Zhong, Haihong
Bezabeh, Binyam
Kinneer, Krista
Christie, Ronald J.
Fazenbaker, Christine
Wu, Herren
Gao, Changshou
MOLECULAR PHARMACEUTICS, 2017, 14 (05) : 1501 - 1516

← 1 2 3 4 5 →